Results 231 to 240 of about 250,140 (291)

Sugar, power and policy: The political economy of a health and economic 'win-win' in Fiji's sugar-sweetened beverage tax. [PDF]

Global Health
Elliott LM, Waqa GD, Ravuvu ALA, Dalglish SL, Topp SM.   +4 more
europepmc   +1 more source

The Uppsala APP Mutation Promotes Wild‐Type Amyloid‐β Aggregation and Deposition In Vivo

Advanced Science, EarlyView.
We investigated in vivo cross‐seeding of amyloid‐β (Aβ) isoforms in transgenic mice co‐expressing wild‐typeAβ and the Uppsala‐mutant Aβ variant (AβUpp), lacking six central residues. Weleveraged MALDI‐MS imaging and hyperspectral microscopy to follow spatio‐temporalAβ deposition.
Junyue Ge, María Pagnon de la Vega, Silvia Zampar, Enrica Cerilli, Srinivas Koutarapu, Ling Wu, Paul Fraser, Sertan Arkan, Vilmantas Giedraitis, Lars Lannfelt, Greta Hultqvist, Stina Syvänen, Martin Ingelsson, Jörg Hanrieder, Dag Sehlin   +14 more
wiley   +1 more source

Protocol for quantifying the horizontal and vertical distribution of junctional proteins in fixed epithelial cells. [PDF]

STAR Protoc
Lovejoy M, Mucci CA, Rabino A, Garcia-Mata R.   +3 more
europepmc   +1 more source

KDM4A Erases the H3R17me2a Mark, Facilitating Chromosome Condensation

Advanced Science, EarlyView.
This study reveals a reversible histone modification switch governing chromosome condensation during mitosis. PKCα‐activated KDM4A removes H3R17me2a, permitting Suv39h1‐driven H3K9me3 deposition. This epigenetic transition recruits the chromosomal passenger complex and triggers Aurora B‐dependent H3S10 phosphorylation, coordinating chromatin remodeling
Yena Cho, Jee Won Hwang, Gyu Hwan Hyun, Sangkyu Lee, Dae‐Geun Song, Su‐Nam Kim, Yong Kee Kim   +6 more
wiley   +1 more source

Large extracellular vesicles regulate endothelial angiogenic potential via paracrine and autocrine signaling. [PDF]

J Biol Chem
Richmond G, Nguyen R, Sedgwick A, Schorey JS, D'Souza-Schorey C.   +4 more
europepmc   +1 more source

Allogeneic Immune Cell Perfusion Inhibits the Growth of Vascularized 3D In Vitro Tumor Models, Induces Vascular Regression and Desmoplasia, but Promotes Tumor Cell Invasion

Advanced Science, EarlyView.
This study presents a vascularized 3D tumor model to investigate immune–stromal–tumor interactions under allogeneic PBMC perfusion. While immune cells induced tumor shrinkage, they also promoted vascular regression, stromal activation, and cancer cell invasion.
Alexandra Raab, Rasika Daware, Marcelo A. Szymanski de Toledo, Oskar Weber, Dimitris Kapsokalyvas, Twan Lammers, Horst Fischer, Federica De Lorenzi, Fabian Kiessling   +8 more
wiley   +1 more source

Mayflies of the Fiji Islands (Ephemeroptera). [PDF]

Zookeys
Kaltenbach T.
europepmc   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

Protocol for quantifying vertebral column morphology for the statistical analysis of scoliosis severity in zebrafish. [PDF]

STAR Protoc
Voigt B, Atayeter E, Sistrunk R, Gray RS.   +3 more
europepmc   +1 more source

Mapping the relationship of reef structure and surfer spatial patterns at Cloudbreak, Fiji. [PDF]

Sci Rep
Kapono CA, Pascoe KH, Kane HH, Cortes M, Ferreira SB, Pascoe M, Hacker A, Ryan F, Ninomoto BK, Steward KK, Stark-Kinimaka M, Nakoa Iii JWP, Burns JHR.   +12 more
europepmc   +1 more source