Results 41 to 50 of about 250,140 (291)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Fiji Times hits back at PM's allegations
Pacific Journalism Review, 2000 'Most of the Prime Minister's statements consisted of sweeping generalisations or statements of opinion dressed up as fact—ironically, the very sin of which he accused the media.'
The Fiji Times
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Collaborating With Communities: Citizen Science Flood Monitoring in Urban Informal Settlements
Urban Planning, 2021 Concerns regarding the impacts of climate change on marginalised communities in the Global South have led to calls for affected communities to be more active as agents in the process of planning for climate change.
Erich Wolff +4 more
doaj +1 more source
Book Review: Language Planning and Policy in the Pacific, Vol. 1: Fiji, The Philippines and Vanuatu by Richard B. Baldauf, Jr. and Robert B. Kaplan [PDF]
, 2008 RICHARD B. BALDAUF JR. AND ROBERT B. KAPLAN (Eds.). Language Planning and Policy in the Pacific, Vol. 1: Fiji, The Philippines and Vanuatu. Clevedon, UK: Multilingual Matters Ltd., 2006. pp. 239. Hb £ 34.95.
Shrestha, Prithvi
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Students’ perception of a reduction in teaching weeks in a medical programme in Fiji
The Asia Pacific ScholarIntroduction: The MBBS programme at Fiji National University reduced its teaching weeks from 18 to 14 weeks in 2018. The purpose of this study was to assess student perceptions of learning and teachers following the reduction in the number of teaching ...
Rachael Tufui Masilomani +9 more
doaj +1 more source
Unique Opportunities of Island States to Transition to a Low-Carbon Mobility System [PDF]
, 2020 Small islands developing states (SIDS) contribute minuscule proportions to global greenhouse gas (GHG) emissions and energy consumption, but are highly exposed to climate change impacts, in particular to extreme weather events and sea-level rise. However,
Blechinger, Philipp +2 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source