Results 191 to 200 of about 17,078 (216)
Some of the next articles are maybe not open access.
1999
Abstract Filaggrin is named for its ability to cause intermediate filament aggregation in vitro. It is one of the original proteins recognized as an ‘intermediate filament-associated protein’ or IFAP. Filaggrin is expressed by keratinocytes of epidermis and other cornified epithelia as the cells undergo terminal differentiation and form ...
Beverly A Dale, Richard B Presland
openaire +1 more source
Abstract Filaggrin is named for its ability to cause intermediate filament aggregation in vitro. It is one of the original proteins recognized as an ‘intermediate filament-associated protein’ or IFAP. Filaggrin is expressed by keratinocytes of epidermis and other cornified epithelia as the cells undergo terminal differentiation and form ...
Beverly A Dale, Richard B Presland
openaire +1 more source
Allergo Journal, 2009
Profilaggrin stellt ein Schlusselprotein in der Hornschicht der Haut dar. Wahrend der Differenzierung der Keratinozyten wird es proteolytisch in 10–12 Filaggrin-Monomere gespalten, die fur die Bundelung der Keratinintermediarfilamente zu Makrofibrillen sorgen.
Stephan Weidinger +2 more
openaire +1 more source
Profilaggrin stellt ein Schlusselprotein in der Hornschicht der Haut dar. Wahrend der Differenzierung der Keratinozyten wird es proteolytisch in 10–12 Filaggrin-Monomere gespalten, die fur die Bundelung der Keratinintermediarfilamente zu Makrofibrillen sorgen.
Stephan Weidinger +2 more
openaire +1 more source
Pathologie-biologie, 1989
Cells in the granular layer of mammalian epidermis contain densely staining bodies called keratohyalin granules. Two types of granules are identified. Larger ones contain phosphorus and consist largely of an unusually histidine rich protein. This protein has a high molecular weight and contains a large fraction of basic aminoacids.
Y, Sarret +3 more
openaire +1 more source
Cells in the granular layer of mammalian epidermis contain densely staining bodies called keratohyalin granules. Two types of granules are identified. Larger ones contain phosphorus and consist largely of an unusually histidine rich protein. This protein has a high molecular weight and contains a large fraction of basic aminoacids.
Y, Sarret +3 more
openaire +1 more source
Detection of New Epitopes of Antibodies to Filaggrin in Filaggrin Protein Molecule
Bulletin of Experimental Biology and Medicine, 2011Immunogenic characteristics of filaggrin protein molecule as an antigen for antibodies to filaggrin, markers of early rheumatoid arthritis, were studied. Two new peptide motives, possible epitopes for antibodies to filaggrin, were shown in the filaggrin molecule by predictive analysis using programmed algorithms.
A G, Kobylyansky +5 more
openaire +2 more sources
Filaggrin and Skin Barrier Function
2016The skin barrier function is greatly dependent on the structure and composition of the uppermost layer of the epidermis, the stratum corneum (SC), which is made up of flattened anucleated cells surrounded by highly organized and continuous lipid matrix.
Kezic, Sanja, Jakasa, Ivone
openaire +3 more sources
Keratin and filaggrin expression in keratoacanthoma
Journal of the European Academy of Dermatology and Venereology, 2007AbstractTo clarify the histogenesis of keratoacanthoma, we studied keratin (K) expression in keratoacanthoma (KA) using 10 different anti‐keratin antibodies against K1, K7, K8, K10, K14, K15, K16, K17, K18 and K19 and anti‐filaggrin (filament aggregating protein) antibody.
Yoshiyuki, Ito +7 more
openaire +2 more sources
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1986
It has been shown in recent studies that a group of histidine-rich proteins play a significant role--as interfilamentous matrix proteins--in keratin formation in the epidermis of man and other species. These proteins have been termed filaggrins in reference to their ability to aggregate in vitro reconstituted keratin filaments to macrofibrils with a ...
openaire +1 more source
It has been shown in recent studies that a group of histidine-rich proteins play a significant role--as interfilamentous matrix proteins--in keratin formation in the epidermis of man and other species. These proteins have been termed filaggrins in reference to their ability to aggregate in vitro reconstituted keratin filaments to macrofibrils with a ...
openaire +1 more source
Atopic Eczema and the Filaggrin Story
Seminars in Cutaneous Medicine and Surgery, 2008The discovery that null mutations in the filaggrin gene (FLG) are associated with atopic eczema represents the single most significant breakthrough in understanding the genetic basis of this complex disorder. The association has been replicated in multiple independent studies during the past 2 years with the use of various methodologies, from ...
Brown, Sara J., Irvine, Alan D.
openaire +3 more sources
2014
Psoriasis is a chronic inflammatory skin disease of multifactorial origin. A number of psoriasis susceptibility loci are known, and some are shared with susceptibility for atopic dermatitis. This has led to speculation that filaggrin gene (FLG) mutations and changes in filaggrin expression may also be associated with psoriasis.
Peter Jensen, Lone Skov
openaire +1 more source
Psoriasis is a chronic inflammatory skin disease of multifactorial origin. A number of psoriasis susceptibility loci are known, and some are shared with susceptibility for atopic dermatitis. This has led to speculation that filaggrin gene (FLG) mutations and changes in filaggrin expression may also be associated with psoriasis.
Peter Jensen, Lone Skov
openaire +1 more source
Latex allergy and filaggrin null mutations
Journal of Dentistry, 2011Natural rubber latex (NRL) contains over 200 proteins of which 13 have been identified as allergens and the cause of type I latex allergy. Health care workers share a high occupational risk for developing latex allergy. Filaggrin null mutations increase the risk of type I sensitizations to aeroallergens and it is possible that filaggrin null mutations ...
Carlsen, Berit C +8 more
openaire +3 more sources