Results 31 to 40 of about 23,872 (126)

Change in Composition of the Anopheles Gambiae Complex and its Possible Implications for the Transmission of Malaria and Lymphatic Filariasis in North-Eastern Tanzania. [PDF]

open access: yes, 2012
A dramatic decline in the incidence of malaria due to Plasmodium falciparum infection in coastal East Africa has recently been reported to be paralleled (or even preceded) by an equally dramatic decline in malaria vector density, despite absence of ...
Simonsen, Paul E   +13 more
core   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

open access: yesInterdisciplinary Medicine, Volume 4, Issue 4, July 2026.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione   +2 more
wiley   +1 more source

Will mass drug administration eliminate lymphatic filariasis? Evidence from northern coastal Tanzania [PDF]

open access: yes, 2012
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and 85 reproduction in any medium, provided the original author and source
Allen, Tim   +3 more
core   +1 more source

Critical role of keratinocytes and protease‐activated receptor 2 in secondary lymphedema development

open access: yesClinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Activated keratinocytes play an important role in the early stage of the pathophysiology of secondary lymphedema through PAR2 signaling. Lymphatic injury‐induced protease activation stimulates keratinocyte PAR2 signaling, driving hyperkeratosis and Th2 inflammation, which can be therapeutically attenuated by teriflunomide. Abstract Background Secondary
Hyeung Ju Park   +18 more
wiley   +1 more source

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

open access: yesJournal of Applied Toxicology, Volume 46, Issue 6, Page 1856-1870, June 2026.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz   +3 more
wiley   +1 more source

Targeting Mitochondria in Aging‐Related Diseases: Therapeutic Potential and Obstacles

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This article systematically summarized the specific mechanism of aging‐related diseases caused by mitochondrial dysfunction, and summarized the broad‐spectrum treatment methods and disease targeted treatment strategies for mitochondria. At the same time, it also pointed out the dilemma faced by mitochondrial targeted treatment.
Zijie Xiang   +12 more
wiley   +1 more source

An inquiry‐based activity to teach about insects of medico‐legal importance: Lessons from Redi's landmark experiment

open access: yesNatural Sciences Education, Volume 55, Issue 1, June 2026.
Abstract In this article, we describe an inquiry‐based teaching activity developed in a public high school in Brazil. The objectives were to (a) develop an experimental activity grounded on the students’ autonomy for formulating and testing hypotheses, (b) address Biology topics from a historical and multidisciplinary perspective, (c) stimulate skills ...
Simão Dias Vasconcelos   +1 more
wiley   +1 more source

The Abundant Larval Transcript-1 and -2 Genes ofBrugia malayi Encode Stage-Specific Candidate Vaccine Antigens for Filariasis [PDF]

open access: yes, 2000
Lymphatic filariasis is a major tropical disease caused by the mosquito-borne nematodes Brugia and Wuchereria. About 120 million people are infected and at risk of lymphatic pathology such as acute lymphangitis and elephantiasis.
Allen, Judith   +4 more
core  

Filariasis in Travelers Presenting to the GeoSentinel Surveillance Network [PDF]

open access: yes, 2007
Background: As international travel increases, there is rising exposure to many pathogens not traditionally encountered in the resource-rich countries of the world.
Law, Melissa A.   +64 more
core   +2 more sources

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