Results 121 to 130 of about 1,293,810 (280)

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan   +12 more
wiley   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu   +4 more
wiley   +1 more source

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

open access: yesAdvanced Healthcare Materials, EarlyView.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen   +9 more
wiley   +1 more source

FROM CAD MODEL TO 3D PRINT VIA “STL” FILE FORMAT [PDF]

open access: yesFiabilitate şi Durabilitate, 2010
The paper work presents the STL file format, which is now used for transferring information from CAD software to a 3D printer, for obtaining the solid model in Rapid prototyping and Computer Aided Manufacturing.
Cătălin IANCU   +2 more
doaj  

Crypt4GH: a file format standard enabling native access to encrypted data. [PDF]

open access: yesBioinformatics, 2021
Senf A   +6 more
europepmc   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su   +8 more
wiley   +1 more source

Pairs and Pairix: a file format and a tool for efficient storage and retrieval for Hi-C read pairs. [PDF]

open access: yesBioinformatics, 2022
Lee S   +4 more
europepmc   +1 more source

Inventory routing and on-line inventory routing file format

open access: yes, 2011
This document presents a simple extension of the TSPLIB file format to serve our needs in the Inventory Routing Problem types. Instead of creating a new file format or putting ASCII files online with a simple description, we have chosen to extend the ...
Geiger, Martin,, Sevaux, Marc
core   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

open access: yesAdvanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong   +12 more
wiley   +1 more source

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