Results 201 to 210 of about 289,055 (256)

Alignoth: portable and interactive visualization of read alignments. [PDF]

Bioinformatics
Wiegand F, Mölder F, Köster J.
europepmc   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

MHC1-TIP enables single-tube multimodal immunopeptidome profiling and uncovers intratumoral heterogeneity in antigen presentation. [PDF]

Commun Biol
Bathini M, Bocaniciu D, Johnson FD, de Jong RCP, Yu F, Aloi VD, Kuiken MC, Mors JR, Giebel L, Champagne J, Bleijerveld O, Agami R, Dijkstra KK, Thommen DS, Nesvizhskii AI, Lindeboom RGH.   +15 more
europepmc   +1 more source

Modulating Purothionin Accumulation and Signal Peptide Cleavage Fine‐Tunes Wheat Flour Gluten Properties to Improve Cookie‐Making Quality

Advanced Science, EarlyView.
Dual genetic strategies for improving wheat processing quality by regulating purothionin accumulation to modulate gluten quantity and quality. The first strategy involves targeting signal peptide (SP) cleavage sites (e.g., through mutation) to indirectly reduce gluten content, thereby disrupting gluten network formation.
Yijie Liu, Siyuan Chang, Zhaoheng Zhang, Tianqi Kang, Mingde Liu, Yuan Zong, Fei Ni, Yinguang Bao, Ruijie Zhang, Xiaobang Zhang, Jinkun Du, Mingming Xin, Zhaorong Hu, Jie Liu, Zhongfu Ni, Qixin Sun, Yingyin Yao   +16 more
wiley   +1 more source

Transcriptomic data of seven flax varieties contrasting in lodging resistance. [PDF]

Front Plant Sci
Krupskaya DA, Pushkova EN, Krasnova VA, Krasnov GS, Rozhmina TA, Rybakova TY, Arkhipov AA, Barsukov NM, Moskalenko OD, Kovalenko VL, Sigova EA, Dvorianinova EM, Borkhert EV, Dmitriev AA, Melnikova NV.   +14 more
europepmc   +1 more source

Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine‐Dependent Pro‐Inflammatory Immune Microenvironment

Advanced Science, EarlyView.
T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu, Bixia Wang, Xinya Jiang, Fangqing Zhang, Qianqian Huang, Xinyi Wu, Shuang Fan, Qi Zhang, Jingrui Zhou, Jianing Tang, Xiao‐Dong Mo, Yu Wang, Ying‐Jun Chang, Huidong Guo, Xiao‐Jun Huang   +14 more
wiley   +1 more source

Non-destructive DNA extraction for recovering mitochondrial genomes from museum grasshopper specimens. [PDF]

PLoS One
Tang H, Zou J, Zhang K, Huang H.
europepmc   +1 more source

Guiding Similarity Search in Chemical Fragment Spaces with Weighted Fingerprints. [PDF]

J Chem Inf Model
Lübbers J, Schokolowski M, Lessel U, Weber A, Rarey M.   +4 more
europepmc   +1 more source

Residues neighboring an SH3-binding motif participate in the interaction in vivo. [PDF]

Genetics
Jordan DF, Dubé AK, Dionne U, Bradley D, Landry CR.   +4 more
europepmc   +1 more source

PROTAC-PatentDB: A PROTAC Patent Compound Dataset. [PDF]

Sci Data
Cai H, Yao G, Shi Y, Zhang T, Hu Y.
europepmc   +1 more source