Results 101 to 110 of about 4,134,428 (339)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

FragTracer: Real-Time Fragmentation Monitoring Tool for F2FS File System. [PDF]

Sensors (Basel), 2023
Cho M, Kang D.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Silvabase: A flexible data file management system [PDF]

The need for a more flexible and efficient data file management system for mission planning in the Mission Operations Laboratory (EO) at MSFC has spawned the development of Silvabase.
Lambing, Steven J., Reynolds, Sandra J.
core   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

A quantitative comparison of apically extruded debris during root canal preparation using NiTi full-sequence rotary and single-file rotary systems: An in vitro study

Endodontology
Aim: The purpose of this study was to compare quantitatively the apically extruded debris during root canal preparation using NiTi full-sequence rotary and single-file rotary systems.
Pallavi Goel, R. Vikram, R. Anithakumari, M. S. Adarsha, M. E. Sudhanva   +4 more
doaj   +1 more source

The effect of different kinematics on apical debris extrusion with a single-file system. [PDF]

Odontology, 2023
Al Omari TMN, La Rosa GRM, Albanna RHI, Tabnjh A, Papale F, Pedullà E.   +5 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Formal verification of a concurrent file system based on lock guarantee conditions extended concurrent separation logic

Tongxin xuebao
During the formal verification, logic is relied to formally specify and reason about the properties that the file system must satisfy. Concurrent separation logic (CSL) is used in the formal verification of concurrent file systems and to prove the ...
ZHENG Xinmin, LI Mingshu, YANG Qiusong, LI Wenbo   +3 more
doaj  

A Comparative Evaluation of the Apically Extruded Debris from Root Canals Prepared by R-Motion NiTi File System. [PDF]

Int J Dent, 2023
Al-Saffar FB, Al-Gharrawi HA.
europepmc   +1 more source