Results 71 to 80 of about 2,101 (161)

Correction to: Filgotinib: First Approval [PDF]

Drugs, 2021
Dhillon, Sohita, Keam, Susan J.
openaire   +1 more source

Interindividual variability and its impact on the effectiveness of Janus kinase inhibitors in rheumatoid arthritis treatment

Frontiers in Medicine
IntroductionAchieving the primary treat-to-target (T2T) goal in rheumatoid arthritis (RA) remains challenging for many patients, reflecting limitations in the effectiveness of existing treatments. Our study examines factors influencing Janus kinase (JAK)
Cristina Martinez-Molina, Cristina Martinez-Molina, Silvia Vidal, Silvia Vidal, Cesar Diaz-Torne, Cesar Diaz-Torne, Cesar Diaz-Torne, Hye S. Park, Hye S. Park, Hye S. Park, Hèctor Corominas, Hèctor Corominas, Hèctor Corominas   +12 more
doaj   +1 more source

Filgotinib in cutaneous lupus: is a negative positive? [PDF]

Rheumatology, 2021
Kathryn Connelly, Eric F Morand
openaire   +2 more sources

Experimental and Investigational Pharmacotherapy for Psoriatic Arthritis: Drugs of the Future

Journal of Experimental Pharmacology, 2020
Luca Navarini,1,* Damiano Currado,1,* Luisa Costa,2 Marco Tasso,2 Maria Sole Chimenti,3 Francesco Caso2 1Unit of Rheumatology, Immunology and Clinical Medicine, Università Campus Bio-Medico Di Roma, Rome, Italy; 2Rheumatology Unit, Department of ...
Navarini L, Currado D, Costa L, Tasso M, Chimenti MS, Caso F   +5 more
doaj  

Filgotinib: An Extensive Review of a Promising JAK Inhibitor in Rheumatoid Arthritis

Indian Journal of Rheumatology
This review aims to provide a comprehensive analysis of filgotinib, a selective Janus kinase 1 (JAK1) inhibitor, and its potential applications in the treatment of rheumatoid arthritis (RA). It assesses filgotinib’s efficacy, safety, and role compared to
Krishna. S Upadhye, Paritosh Tayade, Hariom Patidar, Narendra Yadav   +3 more
doaj   +1 more source

Refractory Pyostomatitis Vegetans With Multiple Aseptic Cutaneous Abscesses Successfully Treated With Filgotinib in Ulcerative Colitis

JEADV Clinical Practice
We report on a 31‐year‐old male patient diagnosed with active moderate‐to‐severe ulcerative colitis and a history of splenectomy. He was hospitalized due to confluent pustular oral lesions and multiple skin abscesses.
C. Dandoy, D. Franchimont, C. Delvaux, A. Buggenhout, D. Bernardi, V. Del Marmol, J. M. L. White   +6 more
doaj   +1 more source

Filgotinib [PDF]

, 2020
openaire   +1 more source

The efficacy and safety of different Janus kinase inhibitors as monotherapy in rheumatoid arthritis: A Bayesian network meta-analysis.

PLoS ONE
ObjectiveThis study aims to evaluate the efficacy and safety of JAK inhibitors in the treatment of patients with RA.MethodsThe databases CNKI, VIP, Wanfang, CBM, and PubMed, Embase, Cochrane Library and Web of Science were searched to identify relevant ...
Bingjia Qu, Feng Zhao, Ying Song, Junyi Zhao, Yuxin Yao, Yulan Chen, Ruobing Liao, Lingyu Fu   +7 more
doaj   +1 more source

Focus on Filgotinib in Rheumatoid Arthritis: A Trial-Based Review

Mediterranean Journal of Rheumatology
Janus kinases (JAK)/Signal Transducer and Activator of Transcription (STAT) pathway is involved in pathophysiologic cascade of a notable number of rheumatic diseases. The development of JAK inhibitors has expanded treatment choices in rheumatoid arthritis (RA) with a sustained class-effect efficacy.
Skouvaklidou, Elpida, Deligeorgakis, Dimitrios, Skalkou, Anastasia, Skepastianos, Vasileios, Tsafis, Konstantinos, Papadimitriou, Evdokia, Pagkopoulou, Eleni, Avgerou, Paraskevi, Mytilinaiou, Maria G, Tzitiridou-Chatzopoulou, Maria, Kougkas, Nikolaos, Adamichou, Christina   +11 more
openaire   +2 more sources

Filgotinib bei Colitis ulcerosa: ein Review

Journal für Gastroenterologische und Hepatologische Erkrankungen
ZusammenfassungColitis ulcerosa ist eine chronisch entzündliche Darmerkrankung mit Befall des Kolons. Die häufigsten Symptome sind blutige und schleimige Durchfälle, Stuhldrang sowie abdominelle Schmerzen. Diese Symptome stellen für die Betroffenen oft eine wesentliche gesundheitliche Beeinträchtigung dar.Filgotinib ist ein Medikament, das in oraler ...
Blesl, Andreas, Novacek, Gottfried, Reinisch, Walter, Kienbauer, Melanie, Platzer, Reingard, Wolzt, Michael, Koch, Robert, Högenauer, Christoph, Ribarics, Reiner, Moschen, Alexander   +9 more
openaire   +2 more sources