Results 41 to 50 of about 12,641 (263)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Near-Field Simulations of Film Cooling with a Modified DES Model

Inventions, 2020
Modeling the heat transfer characteristics of highly turbulent flow in gas turbine film cooling is important for providing better insights and engineering solutions to the film cooling problem. This study proposes a modified detached eddy simulation (DES)
Feiyan Yu, Savas Yavuzkurt
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Computational study of plasma actuator on film cooling performance for different shaped holes

AIP Advances, 2015
An investigation on film cooling holes with plasma actuators are performed for circular hole, expansion-shaped hole and fan-shaped hole on the surface of flat plate.
Sheng-ji Dai, Yang Xiao, Li-ming He, Tao Jin, Peng-hui Hou, Qian Zhang, Zi-chen Zhao   +6 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Pressure Gradient Effects on Film Cooling [PDF]

Volume 4: Heat Transfer; Electric Power; Industrial and Cogeneration, 1995
Film cooling effectiveness was studied experimentally using a flat plate test facility with a single row of inclined round holes which injected high density, cryogenically cooled air. A pressure distribution representative of the suction side of a gas turbine blade was imposed on the test plate using a top wall contour.
Donald L. Schmidt, David G. Bogard
openaire   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez, Alejandro F. Manchón‐Gordón, Antonio Vidal‐Crespo, Rafael Caballero‐Flores, Jhon J. Ipus, Clara F. Conde   +5 more
wiley   +1 more source

Effects of Flow Oscillations in the Mainstream on Film Cooling

Inventions, 2018
The objective of this study is to investigate the effects of oscillations in the main flow and the coolant jets on film cooling at various frequencies (0 to 2144 Hz) at low and high average blowing ratios.
Seung Il Baek, Savas Yavuzkurt
doaj   +1 more source

Experimental Optimization of the Compound Angled Asymmetric Laidback Fan Shaped Film Cooling Hole

Energies, 2022
In this study, the effect of shape variables on the film cooling effectiveness of the compound angled asymmetric laidback fan shaped hole was experimentally investigated, and the optimum values of select design variables were presented.
Ye Rim Jo, Jin Young Jeong, Jae Su Kwak
doaj   +1 more source