Results 41 to 50 of about 1,277,746 (294)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Identification of Time-Varying Hammerstein-Wiener Systems

open access: yesIEEE Access, 2020
This paper focuses on identifying time-varying Hammerstein-Wiener systems. A modified algorithm based on extended Kalman filter is proposed. The algorithm is derived from the comparison between the first and the second order extended Kalman filter ...
Feng Yu, Zhizhong Mao, Dakuo He
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Geometric Collaborative Filtering with Convergence

open access: yesCoRR
13 pages, 1 figure, 3 ...
Hisham Husain, Julien Monteil
openaire   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Convergence Analysis for an Online Data-Driven Feedback Control Algorithm

open access: yesMathematics
This paper presents convergence analysis of a novel data-driven feedback control algorithm designed for generating online controls based on partial noisy observational data.
Siming Liang   +3 more
doaj   +1 more source

DVL-Aided SINS In-Motion Alignment Filter Based on a Novel Nonlinear Attitude Error Model

open access: yesIEEE Access, 2019
A novel nonlinear attitude error model based on square root cubature information filter (SR-CIF) is proposed aiming to speed up the convergence rate of DVL-aided strapdown inertial navigation system (SINS) in-motion initial alignment for autonomous ...
Lu Zhang   +3 more
doaj   +1 more source

Vehicle Cabin Noise Cancellation Model Using Pre-Filter for Improved Convergence Rate and Better Stability

open access: yesCommunications, 2023
Adaptive algorithms are used in updating the filter coefficients for active noise cancellation applications in reduction of vehicle cabin noise. The performance of the adaptive algorithms in low-frequency noise cancellation depends on how efficiently it ...
Janak Kapoor   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy