Results 41 to 50 of about 1,277,746 (294)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Identification of Time-Varying Hammerstein-Wiener Systems
This paper focuses on identifying time-varying Hammerstein-Wiener systems. A modified algorithm based on extended Kalman filter is proposed. The algorithm is derived from the comparison between the first and the second order extended Kalman filter ...
Feng Yu, Zhizhong Mao, Dakuo He
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Geometric Collaborative Filtering with Convergence
13 pages, 1 figure, 3 ...
Hisham Husain, Julien Monteil
openaire +3 more sources
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Convergence Analysis for an Online Data-Driven Feedback Control Algorithm
This paper presents convergence analysis of a novel data-driven feedback control algorithm designed for generating online controls based on partial noisy observational data.
Siming Liang +3 more
doaj +1 more source
DVL-Aided SINS In-Motion Alignment Filter Based on a Novel Nonlinear Attitude Error Model
A novel nonlinear attitude error model based on square root cubature information filter (SR-CIF) is proposed aiming to speed up the convergence rate of DVL-aided strapdown inertial navigation system (SINS) in-motion initial alignment for autonomous ...
Lu Zhang +3 more
doaj +1 more source
Adaptive algorithms are used in updating the filter coefficients for active noise cancellation applications in reduction of vehicle cabin noise. The performance of the adaptive algorithms in low-frequency noise cancellation depends on how efficiently it ...
Janak Kapoor +3 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

