Results 191 to 200 of about 102,219 (261)

Pelagic food web realignment supports resilient larvae of Southern Bluefin Tuna in a warming ocean. [PDF]

Proc Natl Acad Sci U S A
Landry MR, Laiz-Carrión R, Malca E, Swalethorp R, Décima M, Quintanilla JM, Borrego-Santos R, Davies CH, Kranz SA, Selph KE, Stukel MR, Die D, Beckley LE, Muhling BA, Shiroza A, Kim LE, Cawley GF, Traboni C, Walsh K, Jivanjee A, Matisons L.   +20 more
europepmc   +1 more source

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

Closed Systems for Long-Term Propagation of the Marine Tunicate <i>Botryllus schlosseri</i> Isolated from Natural Seawater. [PDF]

Life (Basel)
Hamar J, Dong W, Luu B, Lin M, Enriquez I, Leprêtre M, Gardell AM, Rinkevich B, Kültz D.   +8 more
europepmc   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Open wide: Identifying North Atlantic right whale feeding behaviour using camera-validated kinematic data and machine learning. [PDF]

PLoS One
Kirkham J, Davies KTA, Foley HJ, Zadra C, Frith R, Segre PS, Fortune SME.   +6 more
europepmc   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Model-Enabled Knowledge Transfer Across Cell Lines, Culture Scales and Conditions. [PDF]

Biotechnol Bioeng
Yu L, Chanona ADR, Kontoravdi C.
europepmc   +1 more source

Differential Effects of Zooplankton on Sunlight Inactivation of Viruses. [PDF]

Environ Sci Technol
Verbel-Olarte MI, Kohn T, Ismail NS.
europepmc   +1 more source

A high-selectivity 24-GHz SIW-DGS-CPW bandpass filter with wide stopband rejection for automotive radar and ADAS. [PDF]

Sci Rep
Abada AM, El-Hameed ASA, Eldamak AR, El-Hennawy HM.   +3 more
europepmc   +1 more source