Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Real-time adaptive filtering of dental drill noise using a digital signal processor [PDF]
The application of noise reduction methods requires the integration of acoustics engineering and digital signal processing, which is well served by a mechatronic approach as described in this paper.
Atherton, MA +3 more
core
Beamforming Techniques for Multichannel audio Signal Separation
Beamforming is a signal processing technique. It has been studied in many areas such as radar, sonar, seismology and wireless communications, to name but a few.
Adel, Hidri +3 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Cyclic Wiener Filtering Algorithm in Discrete Cosine Transform Domain for Vibration Signal
In order to solve the problem that the effect of using cyclic Wiener filter directly to remove the noise on the non-stationary vibration signal is poor, the paper applies discrete cosine transform to the cyclic Wiener filter, proposing the cyclic Wiener ...
Zhang Feng +3 more
doaj +1 more source
Separation and Recovery of Geophysical Signals Based on the Kalman Filter with GRACE Gravity Data
Monthly gravitational field solutions as spherical harmonic coefficients produced by the GRACE satellite mission require post-processing to reduce the effects of shortwave-length noises and north⁻south stripe errors.
Xiaolong Wang +6 more
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Combining accelerometry-based motion artifact cancellation with pulse oximetry processing
This paper proposes a combination of motion artifact (MA) cancellation with pulse oximetry processing. The objectives were to develop motion-resistant pulse oximetry processing relying on using accelerometry-based MA cancellation, and to explore the ...
Theera Leeudomwong +2 more
doaj +1 more source
Mismatched Quantum Filtering and Entropic Information
Quantum filtering is a signal processing technique that estimates the posterior state of a quantum system under continuous measurements and has become a standard tool in quantum information processing, with applications in quantum state preparation ...
Tsang, Mankei
core +1 more source

