Results 121 to 130 of about 843,773 (297)
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
IDEOLOG: A Program for Filtering Econometric Data - A Synopsis of Alternative Methods [PDF]
An account is given of various filtering procedures that have been implemented in a computer program, which can be used in analysing econometric time series.
D.S.G. Pollock
core
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Noise Reduction on G‐Buffers for Monte Carlo Filtering
, 2017 We propose a novel pre‐filtering method that reduces the noise introduced by depth‐of‐field and motion blur effects in geometric buffers (G‐buffers) such as texture, normal and depth images.
Mitchell, Kenny +3 more
core +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Spatial Filtering and Eigenvector Stability: Space-Time Models for German Unemployment Data [PDF]
Regions, independent of their geographic level of aggregation, are known to be interrelated partly due to their relative locations. Similar economic performance among regions can be attributed to proximity.
Michael Tiefelsdorf +3 more
core
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
NOISE-RESISTANCE AND ACCURACY ASSESSMENTS ECG SIGNAL PROCESSING SYSTEMS BASED ON FILTERING METHODS
Измерение, мониторинг, управление, контрольBackground. The accuracy and noise-resistance of an ECG signal processing system is influenced by many factors. But narrow-band low-frequency and broadband electrical interference have a significant impact when recording ECG signals.
Yeldos A. Altay
doaj +1 more source