Results 91 to 100 of about 120,389,537 (218)
Advanced Science, EarlyView.A large‐scale multicenter serum metabolomics study (13 centers, n = 2,149) identified a 9‐metabolite + AFP diagnostic signature for liver cancer (AUC = 0.93). Among the signature, nicotinamide (NAM) was validated as an oncometabolite: NAM enhances NAD+ synthesis, activating SIRT1 to deacetylate and stabilize HIF1α, thereby driving glycolysis, MAPK ...
Yongjie Xu +13 more
wiley +1 more source
Advanced Science, EarlyView.Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kangsan Kim +5 more
wiley +1 more source
In this article we present an introduction to various Filtering algorithms and some of their applications to the world of Quantitative Finance. We shall first mention the fundamental case of Gaussian noises where we obtain the well-known Kalman Filter ...
Javaheri, Alireza +2 more
core
Re‐Thinking Electronic Circuit Design Through Emerging Reconfigurable Field Effect Transistors
Advanced Science, EarlyView.Graphical illustration of reconfigurable field effect transistor (RFET) operation modes, including n‐type, p‐type, and ambipolar transport, as well as their areas of application discussed in this review: digital circuit design, analog circuit design, post‐Shannon computing, and sensing. ABSTRACT Reconfigurable field‐effect transistors, short RFETs, are
Jens Trommer +19 more
wiley +1 more source
An Integrated Artificial Intelligence Framework for Nanomedicine Engineering
Advanced Science, EarlyView.This review outlines a closed‐loop AI ecosystem for nanomedicine engineering. By synergizing multimodal data harmonization, objective‐driven AI architectures, and automated high‐throughput validation, this “Design‐Make‐Test‐Analyze” (DMTA) workflow transforms traditional heuristic formulation into a predictive, self‐optimizing paradigm, accelerating ...
Meichen Dong +10 more
wiley +1 more source
On one-dimensional stochastic control problems: applications to investment models [PDF]
The paper provides a systematic way for finding a partial differential equation that characterize directly the optimal control, in the framework of one?dimensional stochastic control problems of Mayer, with no constraints on the controls.
Ricardo Josa-Fombellida +1 more
core
CW‐Pumped Amplified Spontaneous Emission From Thermally Evaporated CsPbBr3 Films
Advanced Science, EarlyView.Thermally evaporated CsPbBr3 thin films sustain amplified spontaneous emission from short‐pulse toward quasi‐continuous‐wave excitation. Time‐resolved spectroscopy, controlled excitation, and substrate engineering reveal how excitation duration governs optical‐gain stability.
Yuliia Kominko +5 more
wiley +1 more source
The international stock pollutant control: a stochastic formulation with transfers [PDF]
This paper provides a formulation of a stochastic dynamic game that arise in the real scenario of international environmental agreements on the transnational pollution control.
Omar J. Casas, Rosario Romera
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Ecological drivers of the colon cancer microbiome: evidence for niche-based selection over stochastic colonization. [PDF]
Front OncolSu W, Ma ZS.
europepmc +1 more source
Advanced Science, EarlyView.By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo +15 more
wiley +1 more source