Results 111 to 120 of about 120,389,537 (218)

Discretised Non-Linear Filtering for Dynamic Latent Variable Models: with Application to Stochastic Volatility [PDF]

Filtering techniques are often applied to the estimation of dynamic latent variable models. However, these techniques are often based on a set assumptions which restrict models to be specified in a linear state-space form.
Scott I. White, Stan Hurn, Adam E. Clements   +2 more
core  

From sequence to timescale: a frequency-domain control-theoretic framework linking ncRNA sequence composition to epigenetic regulatory timescales. [PDF]

Front Endocrinol (Lausanne)
Boroujerdi M.
europepmc   +1 more source

Advances in Josephson Junction Materials and Processes Toward Practical Quantum Computing

Advanced Science, EarlyView.
Emerging materials for quantum computing, including crystalline materials, two‐dimensional van der Waals materials, two‐dimensional electron gas systems, ferromagnets, and unconventional (e.g., d‐wave) superconductors, offer opportunities to engineer next‐generation Josephson junctions.
Hyunseong Kim, Gyunghyun Jang, Seungwon Jin, Jaewon An, Dongbin Shin, Hyeon‐Jin Shin, Jie Luo, Akel Hashim, Irfan Siddiqi, Yosep Kim, Long B. Nguyen, Hoon Hahn Yoon   +11 more
wiley   +1 more source

In Vivo CRISPR Screen Identifies RPS19 as an Immunotherapy Target in Hepatocellular Carcinoma

Advanced Science, EarlyView.
By employing in vivo CRISPR functional screening, we identify ribosomal protein RPS19 as a pivotal mediator driving immune evasion in hepatocellular carcinoma, wherein tumor‑released RPS19 binds C5aR1 on tumor‑associated macrophages to initiate downstream immunosuppressive signaling; SP94‑peptide‑modified SNPSS nanoparticles deliver Cas9/sgRPS19 ...
Lei He, Duo Yu, Fei Xie, Kaisheng Hou, Zhaozhao Li, Meifang Dai, Jingyi Yun, Haiyan Cao, Yang Xiao, Yueyuan Qiu, Gege Shi, Wangqian Zhang, Shuning Wang, Qiang Hao, Jieyu Zhang, Zhaowei Wang, Yingqi Zhang, Kuo Zhang, Jintao Gu, Haichen Du, Meng Li   +20 more
wiley   +1 more source

Imaging Sonar Detection and Occlusion-Corrected Abundance Estimation in High-Density Aquaculture. [PDF]

Sensors (Basel)
Zhao T, Zhang X, He Y, Ma H, Liu Y, Ma Z.   +5 more
europepmc   +1 more source

XChrom: A Cross‐Cell Chromatin Accessibility Prediction Model Integrating Genomic Sequence and Cellular Context

Advanced Science, EarlyView.
XChrom is a deep learning framework that integrates genomic sequence and single‐cell context to predict chromatin accessibility. It generalizes to unseen cells and genomic regions, enabling cross‐sample and cross‐species analysis. Applied to COVID‐19 patient data, XChrom reveals key transcriptional regulatory mechanisms and disease‐associated ...
Yuanyuan Miao, Xuan Liang, Wenwen Zhang, Dongmei Han, Yurun Li, Zhen Wang   +5 more
wiley   +1 more source

Statistical learning of stochastic complex systems via the Yau-Yau nonlinear filter. [PDF]

Innovation (Camb)
Xu S, Wang Y, Wu S, Wang Y, Dong A, Shing-Toung Yau S, Yau ST, Wu R.   +7 more
europepmc   +1 more source

Highly Linear Perovskite Synapses for Neuromorphic Computing

Advanced Science, EarlyView.
Voltage spikes applied to an Au/ACI‐phase perovskite/ITO memristor emulate the ionic signaling of a biological synapse, generating a tunable postsynaptic current. The vertically aligned perovskite film confines iodide‐vacancy migration, enabling highly linear, and symmetric conductance updates with 100 states and 5.5 aJ per event. Such synapses sustain
Zhongwen Sun, Boyu Wan, Zifan Zhang, Zhikai Wang, Xuan Zhao, Haonan Si, Qingliang Liao, Yue Zhang   +7 more
wiley   +1 more source

Synergistic Regulation of Plankton Communities by Polyculture of Grass Carp and Crucian Carp: Seasonal Dynamics and Interaction Networks Based on eDNA. [PDF]

Biology (Basel)
Shao L, Guo H, Zhou Y, Li H, Li W, Wang C, Guo L, Luo K, Shen Z.   +8 more
europepmc   +1 more source

STRIDE: A Sequencing Depth Robust Metric for Sparse Chromosome Conformation Capture Data Comparison

Advanced Science, EarlyView.
A mean first passage time (MFPT)‐based representation transforms sparse Hi‐C contact maps into robust topological representations, preserving biologically meaningful chromatin features and facilitating robust analysis of TADs, chromatin loops, differential chromatin contacts, and sparse single‐cell Hi‐C data.
Bingxiang Xu, Xiaomeng Gao, Weichu Tao, Zhihua Zhang, Feifei Li   +4 more
wiley   +1 more source