Results 41 to 50 of about 1,444 (254)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A direct synthesis method of multi‐port filtering power divider with arbitrary phase shift, power division and reference impedances

IET Microwaves, Antennas & Propagation, 2023
In this study, a direct synthesis approach is proposed to extract the coupling matrix of multi‐port filtering power divider (FPD) with arbitrary phase shift, power division as well as reference impedances, for the first time.
Gang Zhang, Minghan Shu, Kam Weng Tam, Wang Chen, Wanchun Tang, Jiquan Yang   +5 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Design and Optimization of an Ultra-Low-Power Cross-Coupled LC VCO with a DFF Frequency Divider for 2.4 GHz RF Receivers Using 65 nm CMOS Technology

Journal of Low Power Electronics and Applications, 2023
This article presents the design and optimization of a tunable quadrature differential LC CMOS voltage-controlled oscillator (VCO) with a D flip-flop (DFF) frequency divider.
Muhammad Faisal Siddiqui, Mukesh Kumar Maheshwari, Muhammad Raza, Aurangzeb Rashid Masud   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Wideband Half-Mode SIW Power Divider With Improved Output Isolation Using Slotline Isolation Technology

IEEE Access, 2018
A wideband half-mode substrate integrated waveguide (HMSIW) power divider with bandpassfiltering response using the slotline isolation technology is presented in this paper.
Kaijun Song, Maoyu Fan, Yong Fan
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Novel Wideband Microstrip Filtering Power Divider Using Multiple Resistors for Port Isolation

IEEE Access, 2019
In this paper, a novel wideband filtering power divider with third-order quasi-Elliptic bandpass response is proposed. Its physical mechanism is revealed by the lumped-element equivalent circuit, such as how its transmission poles and zeros are formed ...
Yucheng Wang, Fei Xiao, Yu Cao, Yong Zhang, Xiaohong Tang   +4 more
doaj   +1 more source

A Miniaturized Balanced-to-Unbalanced In-Phase Filtering Power Divider With Wide Upper Stopband and Wideband Common-Mode Suppression

IEEE Access, 2021
A miniaturized balanced-to-unbalanced in-phase filtering power divider with wide upper stopband and wideband common-mode suppression is proposed. The in-phase feature is realized by the coupled/non-coupled lines.
Zhongbao Wang, Zihui Zhu, Ye Fu, Peng Han, Hongmei Liu, Shaojun Fang   +5 more
doaj   +1 more source