Results 81 to 90 of about 4,278,269 (319)

Use of bremsstrahlung radiation to identify hidden weak beta- sources: feasibility and possible use in radio-guided surgery

open access: yes, 2017
The recent interest in beta- radionuclides for radio-guided surgery derives from the feature of the beta radiation to release energy in few millimeters of tissue.
Bocci, V.   +13 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

4-YEAR FOLLOW UP OF PATIENTS AFTER GONIOTREPANATION

open access: yesZdravniški Vestnik, 2002
Background. To present the success of goniotrepanation in patients with glaucoma 4 years after surgery.Methods. We performed follow-up of 32 patients (50 eyes), who had undergone Fronimopoulus goniotrepanation without use of antimetabolites in our ...
Mojca Hudovernik, Dušica Pahor
doaj  

Direct and indirect orthotic management of medial compartment osteoarthritis of the knee [PDF]

open access: yes, 2006
Osteoarthritis (OA) is a painful condition and affects approximately 80% of individuals by the age of 55 [1], with knee OA occurring two times more frequently than OA of the hand or hip [2].The condition is more prevalent in the medial compartment and ...
Altman   +14 more
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

INADEQUATE REPARATIVE REGENERATION IN FISTULAZING GLAUCOMA SURGERY

open access: yesОфтальмохирургия, 2015
Purpose. To reveal predictors of development and clinical manifestations of the syndrome of inadequate reparative regeneration after the fistulazing glaucoma surgery.Material and methods.
N. V. Volkova   +3 more
doaj  

Real-time adaptive filtering of dental drill noise using a digital signal processor [PDF]

open access: yes, 2006
The application of noise reduction methods requires the integration of acoustics engineering and digital signal processing, which is well served by a mechatronic approach as described in this paper.
Atherton, MA   +3 more
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Feature Lines for Illustrating Medical Surface Models: Mathematical Background and Survey

open access: yes, 2015
This paper provides a tutorial and survey for a specific kind of illustrative visualization technique: feature lines. We examine different feature line methods.
A. Chu   +24 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

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