Results 41 to 50 of about 505,456 (266)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Hacia una apelación óptima: acceso y gerenciamiento de la segunda instancia

Revista Direito GV
Resumen La atención que los tribunales de alzada en apelación pueden prestar a los casos que conocen se ha convertido en un “recurso escaso”. Aplicando la metodología del Análisis Económico del Derecho combinada con muestras del derecho comparado y ...
Alvaro Javier Pérez Ragone
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Influence of the Main Filter on QRS-amplitude and Duration in Human Electrocardiogram

Measurement Science Review, 2019
Accurate measurement of electrocardiograms (ECG) is critical for effective diagnosis of patient’s cardiac functions. Detailed examination of filters’ effects on ECG accuracy, reproducibility and robustness covering a wide range of available commercial ...
Vranić Ivana, Vranić Ivona, Antić Boris, Stojanović Goran, Al-Salami Hani   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Metal Mesh Metasurfaces as Dual-Band Bandpass Filters for Terahertz Frequencies

Advanced Electromagnetics
In the paper, we propose a new strategy to design of metal mesh filters (MMFs) based on spatial symmetry analysis of bound states in the continuum(BICs) and manipulating and control with resonances, when BICs transformed to the resonances due to spatial
A. Perov
doaj   +1 more source

Voltage Differencing Buffered Amplifier-Based Novel Truly Mixed-Mode Biquadratic Universal Filter with Versatile Input/Output Features

Applied Sciences, 2022
In this paper, a first-of-a-kind mixed-mode universal filter employing three VDBAs and three passive components, is proposed. The filter operates in all four modes and provides all five filter responses, namely voltage-mode (VM), current-mode (CM), trans-
Mohammad Faseehuddin, Norbert Herencsar, Sadia Shireen, Worapong Tangsrirat, Sawal Hamid Md Ali   +4 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Filter This

In the Library with the Lead Pipe, 2011
In the Library with the Lead Pipe welcomes Audrey Barbakoff, a librarian at the Milwaukee Public Library, and Ahniwa Ferrari, Virtual Experience Manager at the Pierce County Library System in Washington, for a point-counterpoint piece on filtering in ...
Audrey Barbakoff
doaj  

An Exploration of Ideals and Filters in Triangle Algebras

Axioms
In the study of algebraic structures related to logical systems, ideals and filters have different meanings and are algebraic notions related to logical provable formulas.
Euclide Noumen, Fabrice Tchoua Yinga, Blaise Blériot Koguep Njionou, Chris Cornelis   +3 more
doaj   +1 more source