Results 51 to 60 of about 1,669,726 (293)
We describe a Bayesian filtering scheme for nonlinear state‐space models in continuous time. This scheme is called Generalised Filtering and furnishes posterior (conditional) densities on hidden states and unknown parameters generating observed data. Crucially, the scheme operates online, assimilating data to optimize the conditional density on time ...
Friston, Karl +3 more
openaire +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
All-Pole Recursive Digital Filters Design Based on Ultraspherical Polynomials [PDF]
A simple method for approximation of all-pole recursive digital filters, directly in digital domain, is described. Transfer function of these filters, referred to as Ultraspherical filters, is controlled by order of the Ultraspherical polynomial, nu ...
Stamenkovic, Negovan +2 more
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Knowing How Good Our Searches Are: An Approach Derived from Search Filter Development Methodology
Objective – Effective literature searching is of paramount importance in supporting evidence based practice, research, and policy. Missed references can have adverse effects on outcomes.
Sarah Hayman
doaj
A Mid-Infrared Dual-Band Filter With Ultra-High Resolving Power
A mid-infrared (mid-IR) dual-band filter with ultra-high resolving power is designed and numerically investigated. It is composed of an Al2O3 layer between a gold grating and a CaF2 substrate.
Xin He +4 more
doaj +1 more source
Identifying Mislabeled Training Data
This paper presents a new approach to identifying and eliminating mislabeled training instances for supervised learning. The goal of this approach is to improve classification accuracies produced by learning algorithms by improving the quality of the ...
Brodley, C. E., Friedl, M. A.
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hacia una apelación óptima: acceso y gerenciamiento de la segunda instancia
Resumen La atención que los tribunales de alzada en apelación pueden prestar a los casos que conocen se ha convertido en un “recurso escaso”. Aplicando la metodología del Análisis Económico del Derecho combinada con muestras del derecho comparado y ...
Alvaro Javier Pérez Ragone
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

