Results 71 to 80 of about 1,669,726 (293)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Reduction of effluents from water supply stations to surface water bodies
Journal of Environmental Engineering and Landscape Management, 2005 Polluted water from many water‐supply stations of the Ukraine gets into surface water bodies, trenches and ponds. Such water contains chlororganic compounds and coagulants that fail to biodegrade and get into the human body within the nutrition chain and
Leonid Shevchenko
doaj +1 more source
The Augmented Complex Kernel LMS
, 2011 Recently, a unified framework for adaptive kernel based signal processing of complex data was presented by the authors, which, besides offering techniques to map the input data to complex Reproducing Kernel Hilbert Spaces, developed a suitable Wirtinger ...
Bouboulis, Pantelis +2 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
A Study of Image Upsampling and Downsampling Filters
Computers, 2019 In this paper, a set of techniques used for downsampling and upsampling of 2D images is analyzed on various image datasets. The comparison takes into account a significant number of interpolation kernels, their parameters, and their algebraical form ...
Dragoș Dumitrescu +1 more
doaj +1 more source
NeuroImage, 2008 This note presents a simple Bayesian filtering scheme, using variational calculus, for inference on the hidden states of dynamic systems. Variational filtering is a stochastic scheme that propagates particles over a changing variational energy landscape, such that their sample density approximates the conditional density of hidden and states and inputs.
openaire +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
On Combining Lensing Shear Information from Multiple Filters
, 2007 We consider the possible gain in the measurement of lensing shear from imaging data in multiple filters. Galaxy shapes may differ significantly across filters, so that the same galaxy offers multiple samples of the shear.
Bernstein G M +5 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source