Results 81 to 90 of about 1,387,761 (339)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
EnergiesThis study investigates the energy consumption and losses associated with the gas production process in a condensate gas reservoir-type gas storage system.
Hong Meng +6 more
doaj +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Time series denoising with wavelet transform
Journal of Telecommunications and Information Technology, 2005 This paper concerns the possibilities of applying wavelet analysis to discovering and reducing distortions occurring in time series.Wavelet analysis basics are briefly reviewed.
Bartosz Kozłowski
doaj +1 more source
Multiple defaults and contagion risks [PDF]
, 2009 We study multiple defaults where the global market information is modelled as progressive enlargement of filtrations. We shall provide a general pricing formula by establishing a relationship between the enlarged filtration and the reference default-free
Jiao, Ying
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Alternative versions of the Johnson homomorphisms and the LMO functor
, 2019 Let $\Sigma$ be a compact connected oriented surface with one boundary component and let $\mathcal{M}$ denote the mapping class group of $\Sigma$. By considering the action of $\mathcal{M}$ on the fundamental group of $\Sigma$ it is possible to define ...
Vera, Anderson
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Elimination of gases and contamination from water [PDF]
, 1970 Filtration system with membrane type hydrophilic and hydrophobic filters gives absolute filtration with automatic venting of freed gases, and prevents backward transmission of contamination with no bacterial growth through the filters.
Buck, A. P.
core +1 more source