Results 101 to 110 of about 290,900 (257)

Filtrations for Projective Modules

Bulletin of the London Mathematical Society, 1986
Let G be a finite group, N a normal subgroup of G and k a field. Let \(\tilde G=G/N\). The authors prove that there is a kG-module M such that, whenever L is a \(k\tilde G\)-module which has projective covers Q and \(\tilde Q\) as a kG-module and as a \(k\tilde G\)-module respectively, then Q and \(\tilde Q\otimes M\) have the same composition factors.
Carlson, J, Collins, M
openaire   +3 more sources

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

ANALYSIS OF INFLUENCE OF RUTIN AND GRAVITY ACTION ON THE RENAL EXCRETORY FUNCTION

Наука и инновации в медицине, 2016
Aim - to analyze the effect of rutin on the renal excretory function in the conditions of normogravity and hypergravity. Materials and methods. 9 series of experiments were conducted, including 4 series with the use of a centrifuge of ultra-short radius.
E N Zaitceva, A V Dubishchev, V A Kurkin
doaj   +1 more source

Dead-end filtration of natural organic matter: experimental evidence of critical conditions [PDF]

, 2005
The development of membrane technology has reached a state whereby operational optimisation is becoming the major issue to both researchers and industrial operators.
Jefferson, Bruce, Bessiere, Yolaine, Bacchin, Patrice   +2 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

State-of-the-Art of Filtration and Separation Technologies in Taiwan

, 2014
The Filtration Society Japan Association; The Society of Chemical Engineers Japan; The Solid-Liquid Separation Working Party國際20131031~20131101紙本YTokyo ...
Hwang, Kuo-Jen, 黃國楨
core   +1 more source

Optimising Ventilation Strategies for Improved Driving Range and Comfort in Electric Vehicles

World Electric Vehicle Journal
A car cabin’s small volume makes it vulnerable to discomfort if temperature, humidity, and carbon dioxide levels are poorly regulated. In electric vehicles, the HVAC system draws energy from the car battery, reducing the driving range by several dozen ...
Matisse Lesage, David Chalet, Jérôme Migaud   +2 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source