Results 101 to 110 of about 1,387,761 (339)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Optimising Ventilation Strategies for Improved Driving Range and Comfort in Electric Vehicles
World Electric Vehicle JournalA car cabin’s small volume makes it vulnerable to discomfort if temperature, humidity, and carbon dioxide levels are poorly regulated. In electric vehicles, the HVAC system draws energy from the car battery, reducing the driving range by several dozen ...
Matisse Lesage +2 more
doaj +1 more source
Rudarsko-geološko-naftni Zbornik, 2017 Iron (oxy)hydroxides play an important role in a variety of disciplines, among others, environmental and exploration geochemistry, mineralogy, geology and soil science.
Marija Čambala +2 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A simple filtration technique for obtaining purified human chromosomes in suspension
BioTechniques, 2014 Here we present a simple method for cleaning polyamine human mitotic chromosomes in solution. This was achieved by filtering intact (unburst) nuclei along with both large and small cytoplasmic debris through a series of different pore sized filters. Pure
Mohammed Yusuf +3 more
doaj +1 more source
U Michigan - Glomerular Filtration Rate Determination with Minipump Inulin Clearance v1 [PDF]
, 2019 Jeff Hodgin
openalex +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source