Results 91 to 100 of about 4,004,190 (296)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Influence of Humidity on the Electric Field, Filtration Efficiency, and Flow Velocity in Electret Filter Media: Direct Numerical Simulation

open access: yesAtmosphere
Electret filter media are electrostatically charged during the manufacturing process to activate effective electrical separation mechanisms. In order to investigate the influence of humidity on these mechanisms, the electric field, and filtration ...
Daniel Stoll, Sergiy Antonyuk
doaj   +1 more source

Efficiency of Electret Polycarbonate Nonwovens in Respiratory Protection Against Nanoparticles

open access: yesAUTEX Research Journal, 2017
Toxicological research on the influence of noxious nanoparticles on human health indicates the need to develop efficient protective devices. In particular, this concerns respiratory protective equipment employing filtration nonwovens. This paper presents
Brochocka Agnieszka
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Numerical Comparison of Prediction Models for Aerosol Filtration Efficiency Applied on a Hollow-Fiber Membrane Pore Structure

open access: yesNanomaterials, 2018
Hollow-fiber membranes (HFMs) have been widely applied to many liquid treatment applications such as wastewater treatment, membrane contactors/bioreactors and membrane distillation.
Pavel Bulejko
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Simulation of nano fibers and filtration processes

open access: yes, 2022
S.719-749Nano filtration media have become increasingly interesting for filtration applications. The benefit of using nano fibers is the improvement with respect to filter efficiency and the relatively low pressure drop due to the nano slip.
Cheng, L., Wiegmann, A., Rief, S.
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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