Results 51 to 60 of about 23,142 (227)

Lectins of Mycobacterium tuberculosis – rarely studied proteins

open access: yesBeilstein Journal of Organic Chemistry, 2019
The importance of bacterial lectins for adhesion, pathogenicity, and biofilm formation is well established for many Gram-positive and Gram-negative bacteria.
Katharina Kolbe   +3 more
doaj   +1 more source

Functional Analysis of the Chaperone-Usher Fimbrial Gene Clusters of Salmonella enterica serovar Typhi

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
The human-specific pathogen Salmonella enterica serovar Typhi causes typhoid, a major public health issue in developing countries. Several aspects of its pathogenesis are still poorly understood. S.
Karine Dufresne   +2 more
doaj   +1 more source

Tau‐targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy

open access: yesBrain Pathology, EarlyView.
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown   +7 more
wiley   +1 more source

F9 fimbriae of uropathogenic Escherichia coli are expressed at low temperature and recognise Galβ1-3GlcNAc-containing glycans. [PDF]

open access: yesPLoS ONE, 2014
Uropathogenic Escherichia coli (UPEC) is the leading causative agent of urinary tract infections (UTI) in the developed world. Among the major virulence factors of UPEC, surface expressed adhesins mediate attachment and tissue tropism.
Daniël J Wurpel   +12 more
doaj   +1 more source

Body Condition as a Shared Response to Environment in a Commercially Important Demersal Fish Assemblage

open access: yesFish and Fisheries, EarlyView.
ABSTRACT Measures of an organism's weight at a given length are often considered reliable indicators of energy reserves or ‘condition’, which can be related to fecundity and risk of mortality. Understanding the impact of environmental change on fish condition may therefore inform sustainable management of human activities in marine ecosystems.
Philina A. English   +2 more
wiley   +1 more source

EtcABC, a Putative EII Complex, Regulates Type 3 Fimbriae via CRP-cAMP Signaling in Klebsiella pneumoniae

open access: yesFrontiers in Microbiology, 2019
Biofilm formation by Klebsiella pneumoniae on indwelling medical devices increases the risk of infection. Both type 1 and type 3 fimbriae are important factors in biofilm formation by K. pneumoniae. We found that a putative enzyme II (EII) complex of the
Novaria Sari Dewi Panjaitan   +5 more
doaj   +1 more source

A short peptide derived from late embryogenesis abundant proteins enhances acid tolerance in Escherichia coli via modulation of two‐component regulatory systems

open access: yesThe FEBS Journal, EarlyView.
Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley   +1 more source

Enteropathogenic Escherichia coli O157 Strains from Brazil

open access: yesEmerging Infectious Diseases, 2003
We describe two serogroup O157 Escherichia coli strains from Brazilian infants with diarrhea. A variety of assays indicate that these strains belong to the enteropathogenic, not the enterohemorrhagic, pathotype.
T. Eric Blank   +5 more
doaj   +1 more source

Modeling fimbriae mediated parasite–host interactions

open access: yesJournal of Theoretical Biology, 2010
Type 1 fimbriae are a known virulence factor in a number of pathogenic enterobacteriaceae, including Salmonella, Shigella and E. coli. Yet, they are also expressed by some commensal strains, notably of E. coli. One hypothesis of the role of fimbriae in commensals is that they evoke a small but tolerable host immune response in order to have the host ...
Chu, Dominique, Barnes, David J.
openaire   +2 more sources

Helical structure of Bordetella pertussis fimbriae [PDF]

open access: yesJournal of Bacteriology, 1986
The helical structures of Bordetella pertussis fimbriae of serotypes 2 and 6 were determined by optical diffraction analysis of electron micrographs of negatively stained paracrystalline bundles of purified fimbriae. The fimbrial structure is based on an axial repeat of 13 nm that contains five repeating units in two complete turns of a single-start ...
A C, Steven   +5 more
openaire   +2 more sources

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