Results 121 to 130 of about 507,695 (247)

An unexpected uro-digestive connection: pyelosigmoid fistula in an ectopic pelvic kidney. [PDF]

open access: yesJ Surg Case Rep
Ouaddane Alami R   +6 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Does Fisher hypothesis hold for the East Asian Economies? an application of panel unit root tests [PDF]

open access: yes
This study provides evidence supportive of Fisher hypothesis in East Asian economies using panel unit root tests, which allow for the consideration of cross-country interdependence of real interest rates in the estimation.
Ling, Tai-Hu   +2 more
core   +1 more source

Minimally invasive pulmonary valve replacement via left anterior mini-thoracotomy using an automated fastener-assisted suturing technique: a case report. [PDF]

open access: yesJ Surg Case Rep
Lee JA   +11 more
europepmc   +1 more source

Design of an automated radiator panel rotating machine : final design report

open access: yes, 2012
Micro Tool and Machine Ltd. (MTM) required our team to conceptualize and design a machine assembly process capable of moving and orientating transformer radiator cooling panels between two machine operations and in so doing expand the client’s current product line. The team’s proposed machine design is intended to address all of MTM’s design challenges.
Gagnon, Denis   +3 more
openaire   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy