Results 71 to 80 of about 2,690,910 (310)

Optimization of the Forcing Term for the Solution of Two-Point Boundary Value Problems

open access: yesJournal of Mathematics, 2013
We present a new numerical method for the computation of the forcing term of minimal norm such that a two-point boundary value problem admits a solution. The method relies on the following steps.
Gianni Arioli
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

An Impact of Improvement-Exchange Heuristics to Quality of Probabilistic TSP Solution

open access: yesCommunications, 2003
This paper deals with a probabilistic travelling salesman problem (PTSP), which differs from a travelling salesman problem (TSP) [6] in the demand for a customer visit. In PTSP is each customer visited with a given probability only. An objective function
Jaroslav Janacek, Juraj Hurtik
doaj   +1 more source

The Joint Law of the Extrema, Final Value and Signature of a Stopped Random Walk [PDF]

open access: yes, 2014
A complete characterization of the possible joint distributions of the maximum and terminal value of uniformly integrable martingale has been known for some time, and the aim of this paper is to establish a similar characterization for continuous ...
Moritz Duembgen, L. Rogers
semanticscholar   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Multipoint Initial-Final Value Problem for Hoff Equation in Quasi-Sobolev Spaces

open access: yesJournal of Computational and Engineering Mathematics, 2017
Summary: We consider an analog of the linear Hoff equation in quasi-Sobolev spaces with multipoint initial-final value condition. The research is based on the abstract results obtained for the Sobolev type equation with multipoint initial-final value condition in the quasi-Banach spaces of sequences.
Solov'ëva, Natal'ya Nikolaevna   +1 more
openaire   +2 more sources

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Existencia y Dependencia Continua de la Solución de la Ecuación de Onda no Homogénea en Espacios de Sobolev Periódico

open access: yesSelecciones Matemáticas, 2020
In this article, we first prove that the initial value problem associated to the homogeneous wave equation in periodic Sobolev spaces has a global solution and the solution has continuous dependence with respect to the initial data, in [0; T], T > 0.
Yolanda Santiago Ayala   +1 more
doaj   +1 more source

Degradation of Performance Index Value to LQ Control Problem of Optimal Origin Reached LQ Control Problem [PDF]

open access: yes, 2007
In the optimal LQ control problem where the performance index value of quadratic form is minimized, the state value in final stage is not always reachable on the origin.
Hashimoto, Syusuke   +10 more
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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