Results 111 to 120 of about 139,236 (284)
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Suprimir para quienes egresen de la Universidad Argentina John F. Kennedy a partir de la fecha de la presente Resolución las pruebas finales de capacidad profesional establecidas por el art.18 del decreto 08472 ...
RAJNERI [Ministro]
core
Contienes las propuestas realizadas por los participantes del PRIMER ENCUENTRO UNIVERSITARIO DE INFORMÁTICA JURÍDICA.
Gabriel Restrepo
doaj
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Remarques finales. In: Bulletin de l'Association française pour l'étude du quaternaire, vol. 11, n°3-4, 1974. Quaternaire et préhistoire de la Somme et de la Basse Seine. pp.
core +1 more source
En este trabajo se estudia la eficacia de la finalización del ataque en los momentos finales de partidos igualados de balonmano de alto nivel. Para ello se analizaron los diez minutos finales de 55 partidos pertenecientes a los CM 2011 y JJOO 2012 de ...
Andrés González Ramírez +4 more
doaj

