Results 121 to 130 of about 121,557 (289)
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
En este trabajo se estudia la eficacia de la finalización del ataque en los momentos finales de partidos igualados de balonmano de alto nivel. Para ello se analizaron los diez minutos finales de 55 partidos pertenecientes a los CM 2011 y JJOO 2012 de ...
Andrés González Ramírez +4 more
doaj
Se pregunta si los libros de notas finales requieren la firma para su ...
Gaitán Nieto, Liliana
core
[Paradigm shift in modern palliative care: the need for a multidimensional approach]. [PDF]
Prats Orvay M, Lozano A.
europepmc +1 more source
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Suprimir para quienes egresen de la Universidad Argentina John F. Kennedy a partir de la fecha de la presente Resolución las pruebas finales de capacidad profesional establecidas por el art.18 del decreto 08472 ...
RAJNERI [Ministro]
core
[Telegeriatrics for chronic disease management through polypharmacy reduction in primary health careTelegeriatria para o controle de doenças crônicas por meio da redução da polifarmácia na atenção primária à saúde]. [PDF]
Ponce S +3 more
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
La agricultura y la industria españolas de finales del XVIII: Campomanes y Jardine
The present paper deals with the main economic trends of the late Eighteenth Century and their adaptation to Spain during the reigns of Charles III and Charles IV.
Pérez Berenguel, José Francisco
core
[Management by objectives and funding of primary care teams: Critical reflections]. [PDF]
Bayona-Huguet X +2 more
europepmc +1 more source

