Results 51 to 60 of about 2,695,295 (266)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Newsletter / House of Finance, Goethe-Universität Frankfurt 3/10 [PDF]
, 2010 ECB Interest Rate Policy and the "Zero Lower Bound" ; Exploring Qualitative Data in the Financial Domain : Utilizing Machine Learning Techniques ; The Role of Deferred Life Annuities in the Portfolios of Private Households ; Corporate Governance, Market ...
House of Finance
core
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Should Bitcoin Be Classified as Money?
Journal of Social Ontology, 2022 The advent of virtual currencies such as bitcoin raises a pressing question for lawmakers, regulators, and judges: should bitcoin and other virtual currencies be classified as money or currency for legal and regulatory purposes?
Asya Passinsky
doaj
Newsletter / House of Finance, Goethe-Universität Frankfurt 1/11 [PDF]
, 2011 Editorial: Michael Heise : The Chief Economist of Allianz SE about the economic outlook for 2011 Research Finance: Andreas Hackethal, Utpal Bhattacharya, Benjamin Loos, Simon Kaesler, Steffen Meyer : "Unbiased Financial Advice – Wanted but not Followed ...
House of Finance
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Estimate of revenues from the value added tax in the Republic of Croatia [PDF]
, 1997 This Occasional Paper is part of a research project undertaken by the Institute of Public Finance and financed by the Ministry of Finance of the Republic of Croatia.
Kulis, Danijela, Miljenovic, Zarko
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Why Do Countries Matter so Much in Corporate Social Performance? [PDF]
, 2016 Why do levels of corporate social performance (CSP) differ so much across countries? We answer this question in an examination of CSP ratings of more than 2,600 companies from 36 countries.
Cai, Ye, Pan, Carrie, Statman, Meir
core +2 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source