Results 61 to 70 of about 264,809 (268)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The recent financial crisis has triggered a series of failures of many conventional banks and led to the rise of the interest in the Islamic banks. In this study, we seek to address the following question: What was the effect of the financial crisis and ...
Ameni GHENIMI +2 more
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
La ética ha realizado un progreso decisivo desde el día en que reconoció que el valor moral del acto humano no se mide directamente por la rectitud objetiva de la acción o por su resultado; sino por la rectitud del querer. Ciertamente, desde Aristóteles
Joseph de Finance +2 more
doaj +1 more source
Financing Experimentation [PDF]
Entrepreneurs must experiment to learn how good they are at a new activity. What happens when the experimentation is financed by a lender? Under common scenarios, i.e., when there is the opportunity to learn by “starting small” or when “noncompete” clauses cannot be enforced ex post, we show that financing experimentation can become harder precisely ...
Mikhail Drugov, Rocco Macchiavello
openaire +3 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Applying big data technologies in the financial sector – using sentiment analysis to identify correlations in the stock market [PDF]
The aim of this article is to introduce a system that is capable of collecting and analyzing different types of financial data to support traders in their decision - making.
Eszter Katalin Bognár
doaj
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Journal of Academic Finance wishes to acknowledge the following individuals for their assistance with peer review of manuscripts for this issue. We greatly appreciate their help and contributions maintaining the quality of the journal.
jamel Eddine HENCHIRI
doaj

