Results 61 to 70 of about 1,476,605 (287)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Fact or Fake? How News Title, Sentiment and Writing Style help AI to detect COVID-19 Fake News?

open access: yesApplied Artificial Intelligence
This research presents a sophisticated model aimed at detecting COVID-19 related misinformation in Traditional Chinese, a critical response to the swift spread of fake news during the pandemic.
Chen-Shu Wang   +3 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Reconfiguration of financial system elements to restore economic growth : the system simplicity and transformation towards state-based and corporate-based types [PDF]

open access: yes, 2017
Since subprime mortgage crisis of 2008, financial system has no longer driven economies; zero or small GDP dynamics was only maintained by massive sovereign borrowings.
Anureev, Sergey Vladimirovitch
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Analisis Sistem Informasi Manajemen Daerah (Simda) Keuangan pada Dinas Pendapatan, Pengelolaan Keuangan dan Aset Daerah (Ppkad) Kabupaten Lahat [PDF]

open access: yes, 2016
This research discussed about the analysis of regional management information system (SIMDA) for finance at Dinas Pendapatan, Pengelolaan Keuangan dan Aset Daerah) (PPKAD) of Lahat Regency.
Hakiki, A. (Arista)   +2 more
core  

Evaluasi Kepuasan Mahasiswa terhadap Sistem Informasi Penjadwalan Kuliah Biro Administrasi Umum dan Keuangan Universitas Xyz [PDF]

open access: yes, 2013
One way to identify the success indicator of the use of information systems is conducting a survey of user satisfaction. Measuring the quality of Information Systems of Registration and Lecture Scheduling at the Bureau of Administration and Finance ...
Udiono, T. (Tangkas)
core   +2 more sources

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

TAX INCENTIVES TO BROADEN THE INVESTMENT-SAVING POTENTIAL OF THE FINANCE OF THE POPULATION IN THE PENSION SPHERE

open access: yesRussian Journal of Economics and Law, 2016
Objective: to identify the impact of tax incentives on enhancing the investment-savings potential of the finance of the Russians in the pension sphere. Methods: in this work, a systematic approach was applied to the consideration of the financial and tax
L. V. Grigoryeva
doaj   +1 more source

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