Results 61 to 70 of about 84,910 (247)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
University student finances in 2012 [PDF]
, 2013 Around two-thirds of students have reported incomes below the poverty line as student debt soars by almost 30 per cent in just six years according to the findings of the University Student Finances in 2012 report.Summary:According to Universities ...
Emmaline Bexley
core
Repères d’actualités des finances et de la gestion publiques : Spécial COVID-19 en MARS 2020 [PDF]
, 2022 Chronique d'actualité des finances ...
Bin, Fabrice +5 more
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Repères sur la gestion et les finances publiques en Février 2021 [PDF]
, 2021 Chronique d'actualité des finances ...
Bin, Fabrice +6 more
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Journal of Advanced TransportationInternet of Vehicles can improve driving and riding experience, provide information needs, reduce environmental pollution, and improve transportation efficiency, thereby promoting the rapid development and application of intelligent transportation ...
Jiongen Xiao +4 more
doaj +1 more source
Effects of co-ordination strategies on efficacy in the administration of finances in Early Childhood Development Centres in Uasin-Gishu County, Kenya [PDF]
Journal of Studies in Social Sciences and Humanities, 2017 Early childhood education is the basis upon which all levels of education are anchored. The main purpose of this study was to assess co-ordination as a management strategy and its effects on efficacies in the administration of finances in public ECDE ...
Jane Jelimo Michael Kisii
doaj
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Repères sur la gestion et les finances publiques en Août 2020 [PDF]
, 2020 Chronique d'actualité des finances ...
Bin, Fabrice +5 more
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