Results 71 to 80 of about 175,720 (309)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Yearbook of Swiss Administrative Sciences, 2017 In recent decades, several developments have contributed to a change in the mandate of the Swiss Federal Audit Office (SFAO). The criterion of profitability was added to Article 5 of the Federal Audit Office Act (FAOA) in 1995.
Laurent Crémieux, Claudine Morier
doaj +1 more source
Rapport sur la Bibliothèque nationale de France [PDF]
Rapport n° 2008-M-065-02 sur la Bibliothèque nationale de France par l\u27Inspection générale des ...
Inspection générale des finances
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Repères sur la gestion et les finances publiques en Février 2021 [PDF]
, 2021 Chronique d'actualité des finances ...
Bin, Fabrice +6 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Gouverner (par) les finances publiques
, 2011 Les finances publiques sont au coeur des débats et du fonctionnement des sociétés démocratiques. Pourtant, elles sont peu analysées en termes de pouvoir, de conflits d'acteurs, de choix politiques, de contraintes ou de ressources pour l'action publique ...
Bezes, Philippe, Siné, Alexandre
core +3 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
, 1986 Description based on: 1978-79.Previously classed: C 3.191/2:, C 56.209:Mode of access: Internet.Earlier vols.
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University student finances in 2012 [PDF]
, 2013 Around two-thirds of students have reported incomes below the poverty line as student debt soars by almost 30 per cent in just six years according to the findings of the University Student Finances in 2012 report.Summary:According to Universities ...
Emmaline Bexley
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source