Results 71 to 80 of about 26,371,576 (264)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Analysis of KPMG financial statements [PDF]

open access: yes, 2016
Analiza financijskih izvještaja (horizontalna, vertikalna, analiza financijskih pokazatelja te sustava pokazatelja) kvalitetna je osnovica i polazište planiranja budućeg poslovanja. Cilj ovog završnog rada je analizirati financijska izvješća društva KPMG
Bećirović, Samra
core  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Analysis of Podravka Financial Statments [PDF]

open access: yes, 2017
Analiza financijskih izvještaja (horizontalna, vertikalna, analiza financijskih pokazatelja te sustava pokazatelja) kvalitetna je osnovica i polazište planiranja budućeg poslovanja.
Stipetić, Ana
core  

TAXATION AUDIT, TAX CONTROL AND DUE DILIGENCE OF LARGE ENTERPRISES: STATE, TRENDS, DETERMINANTS OF DEVELOPMENT

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики
The article is to substantiate the essence, divergences and determinants of the evolution of taxation audit, tax control and tax due diligence of large enterprises, and to develop proposals for their improvement.
Nazar Tatenko   +5 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

ANTI-CORRUPTION AUDIT OF COMPANIES AND FORESIGHT ANALYSIS IN TERMS OF THE STATE'S EUROPEAN INTEGRATION ECONOMIC POLICY

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики
The article examines the current problems of spreading corruption in Ukraine. It has been established that corruption is a negative socio-economic phenomenon that restrains the state's economic development, reduces trust in the authorities and ...
Анастасія Майстренко   +5 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Youth, Financial Literacy, and Learning: The Role of In-School Financial Education in Building Financial Literacy

open access: yes, 2012
This brief summarizes the role of in-school financial education in building financial literacy for the ...
Center for Financial Security
core  

AN ANALYSIS OF THE PERCEPTION OF CHARTERED ACCOUNTANT TRAINEES REGARDING ACCESS TO THE ACCOUNTING PROFESSION AND PROFESSIONAL TRAINING NEEDS [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2013
In Romania, the certification of the quality of chartered accountant is accomplished by CECCAR(i). It is conditioned by the completion of the period of initial training.
Bunea Ștefan   +3 more
doaj  

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