Results 71 to 80 of about 964,699 (264)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Financial technology, financial knowledge, and financial attitude of Generation Z: Determinants of financial behavior

open access: yesJournal of Enterprise and Development
Purpose — The aim of this study is to examine the influence of financial technology, financial literacy, and financial attitudes on the financial behavior of Generation Z  within the framework of Society 4.0.
Febrio Andi Prasetyo, Mustaqim Mustaqim
doaj   +1 more source

Value Determinants of Financial Threat Perception: Cultural Codes of Economic Behavior of Russians [PDF]

open access: yesAlterEconomics
This article presents an empirical study of the value, cognitive, and cultural determinants of financial threat perception and economic behavior among Russians.
Maxim A. LAZAREV, Mikhail G. POLOZKOV
doaj   +1 more source

The impact of financial literacy and behavioral biases on financial behavior

open access: yes, 2022
Esta dissertação estuda o comportamento financeiro dos indivíduos portugueses, nomeadamente a sua participação no mercado e a tendência para o efeito disposição (preferência para vender ativos com ganhos e manter em carteira ativos com perdas). Para tal, investiga de que forma a literacia financeira e enviesamentos comportamentais (aversão a perdas e ...
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The impact of financial literacy dimensions on youths' financial well-being [PDF]

open access: yesIndustrija
The purpose of the research is to assess how financial literacy affects young people's well-being in accordance with the Theory of Planned Behavior (TPB).
Susanto Alicia Caitlyn
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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