Results 61 to 70 of about 13,825,758 (295)

A multi‐dimensional assessment of financial hardship of cancer patients using existing health system data

open access: yesCancer Medicine, 2023
Background Existing financial hardship screening does not capture the multifaceted and dynamic nature of the problem. The use of existing health system data is a promising way to enable scalable and sustainable financial hardship screening.
Wen You   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Econometric Modeling to Measure the Efficiency of Sharpe’s Ratio with Strong Autocorrelation Portfolios

open access: yesComplexity, 2022
Sharpe’s ratio is the most widely used index for establishing an order of priority for the portfolios to which the investor has access, and the purpose of this investigation is to verify that Sharpe’s ratio allows decisions to be made in investment ...
Karime Chahuán-Jiménez   +2 more
doaj   +1 more source

Modelling a latent daily Tourism Financial Conditions Index [PDF]

open access: yesInternational Review of Economics & Finance, 2015
Abstract The paper uses daily data on financial stock index returns, tourism stock sub-index returns, exchange rate returns and interest rate differences from 1 June 2001–28 February 2014 for Taiwan to construct a novel latent daily tourism financial indicator, namely the Tourism Financial Conditions Index (TFCI).
openaire   +1 more source

Predicting Covariance Matrices with Financial Conditions Indexes [PDF]

open access: yesSSRN Electronic Journal, 2013
We model the impact of financial conditions on asset market volatility and correlation. We propose extensions of (factor-)GARCH models for volatility and DCC models for correlation that allow for including indexes that measure financial conditions. In our empirical application we consider daily stock returns of US deposit banks during the period 1994 ...
Anne Opschoor   +2 more
openaire   +3 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

ECONOMETRIC RESEARCH OF THE IMPACT OF THE GLOBAL FINANCIAL MARKET CONDITIONS ON THE INDEX RTS OIL & GAS

open access: yesСтатистика и экономика, 2016
Based on the theory of cointegrationfor index RTS oil and gas for three time periods model of the relationship withthe factors of conjuncture in the globalfinancial market were built.
Vadim I. Mitrofanov
doaj   +1 more source

Country- specific characteristics influencing Websites based information disclosure practices [PDF]

open access: yesContabilitate şi Informatică de Gestiune, 2018
This paper aims to examine and explain the Websites- based financial disclosure practices differences between developed European countries. The development of Internet financial reporting (IFR), as a new corporate reporting practice, was rapidly ...
Walid Khoufi, Dhouha Khrifech
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

A composite index-based insurance instrument for managing the financial risk of variable hydrometeorology for electric utilities

open access: yesEnvironmental Research: Energy
Variable hydrometeorological conditions can impact electric utilities’ financial stability. Extreme temperatures often increase electricity demand, raising utility costs, while drought reduces hydropower generation and often reduces revenues, with ...
Yash Amonkar   +5 more
doaj   +1 more source

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