Results 71 to 80 of about 13,825,758 (295)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Financial Conditions Indexes for Canada [PDF]

open access: yes
The authors construct three financial conditions indexes (FCIs) for Canada based on three approaches: an IS-curve-based model, generalized impulse-response functions, and factoranalysis.
Ying Liu   +2 more
core  

Aggregate Price Shocks and Financial Instability: An Historical Analysis [PDF]

open access: yes
This paper presents empirical evidence on the hypothesis that aggregate price disturbances cause or worsen financial instability. We construct two annual indexes of financial conditions for the United States covering 1790-1997, and estimate the effect of
Michael D. Bordo   +2 more
core   +2 more sources

A suggestion for financial condition index for Turkish tourism sector

open access: yesPressacademia, 2019
Purpose- When the economic structures and growth behaviors of the countries are examined, it is seen that the countries with the advantage in the tourism sector have achieved significant role if they give the necessary importance to this sector. It is insufficient and incomplete to consider the issue only in terms of macroeconomic indicators.
ALP, Elcin Aykac   +1 more
openaire   +2 more sources

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Monitoring financial stability: a financial conditions index approach [PDF]

open access: yes
Monitoring financial stability requires an understanding of both how traditional and evolving financial markets relate to each other and how they relate to economic conditions.
Scott Brave, R. Andrew Butters
core  

Alternative Monetary Policy Rules in a Small Open Economy with Financial Frictions: The Case of Korea

open access: yesEast Asian Economic Review, 2011
This paper first shows an empirical result of VAR that Korean economy has experienced a severe economic contraction to an exogenous country spread shock.
Yongseung Jung
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

The financial stress index: identification of systemic risk conditions [PDF]

open access: yes
This paper develops a financial stress index for the United States, the Cleveland Financial Stress Index (CFSI), which provides a continuous signal of financial stress and broad coverage of the areas that could indicate it.
Dieter Gramlich   +4 more
core  

A new index of financial conditions [PDF]

open access: yes, 2014
We use factor augmented vector autoregressive models with time-varying coefficients and stochastic volatility to construct a financial conditions index that can accurately track expectations about growth in key US macroeconomic variables.
Korobilis, Dimitris, Koop, Gary
core   +1 more source

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