Results 251 to 260 of about 698,203 (309)

Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform

open access: yesAdvanced Science, EarlyView.
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng   +5 more
wiley   +1 more source

Reassessing Tuberculosis Treatment Outcomes by Sputum Liquid Culture Testing at the End of Treatment in Karnataka, India. [PDF]

open access: yesCureus
S A   +10 more
europepmc   +1 more source

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