Results 71 to 80 of about 21,802,454 (391)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

ANALYSIS OF LABOR AND LEISURE PRACTICES OF SHADOW SELF-EMPLOYED IN THE PHYSICAL LABOR MARKET IN RUSSIA

open access: yesВестник университета, 2021
Blue-collar self-employment occupies about 23 – 25 % in the structure of the Russian economy and is the most difficult for sociological analysis due to its isolation from the outside world. The most acceptable methods of sociological analysis of the self-
I. A. Yurasov   +3 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Financial Development, Financial Fragility, and Growth [PDF]

open access: yes
This paper attempts to reconcile the apparent contradiction between two strands of the literature on the effects of financial intermediation on economic activity. On the one hand, the empirical growth literature finds a positive effect of financial depth
Norman Loayza, Romain Ranciere
core   +3 more sources

NutBaaS: A Blockchain-as-a-Service Platform

open access: yesIEEE Access, 2019
Blockchain, originated from Bitcoin system, has drawn intense attention from the academic community because of its decentralization, persistency, anonymity and auditability.
Weilin Zheng   +5 more
doaj   +1 more source

Regional financial development and firm growth in Peru [PDF]

open access: yes, 2013
This paper documents the relationship between regional financial development and firm growth in the Peruvian manufacturing sector. In order to control for mutual causality between credit availability and firm growth, industry differences in financial ...
Moron, Eduardo   +2 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Social insurance reform and corporate environmental Investments: Evidence from China

open access: yesInternational Review of Economics & Finance
This study examines the impact of social insurance contributions on corporate environmental investments, using a sample of 1684 firms with 18,503 firm-year observations from China's A-share listed companies between 2007 and 2019. Adopting a quasi-natural
Bingcheng Zou   +3 more
doaj   +1 more source

Determinants of Financial Development [PDF]

open access: yes, 2010
"As the world has witnessed the worst financial crisis and climate crisis of our age, during the period of 2007-2009, the issues surrounding the emergence and development of financial markets and carbon markets is becoming an increasingly significant area of research and debate worldwide.
openaire   +4 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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