Results 171 to 180 of about 943,967 (246)

Optimization of SWCNT‐FET Biosensors by Aptamer Engineering and Toehold‐Mediated Strand Displacement

open access: yesAdvanced Science, EarlyView.
Aptamer‐based single‐walled carbon nanotube (SWCNT) field‐effect transistor (FET) biosensors are developed for label‐free, real‐time biomarker detection. Truncated DNA aptamers enhance sensitivity through improved conformational switching. A toehold‐mediated strand displacement (TMSD) strategy optimizes functionalization and simplifies fabrication. The
Haosen Miao   +8 more
wiley   +1 more source

Refractory Hemorrhage Following Total Knee Replacement Unmasking Acquired Hemophilia A. [PDF]

open access: yesCureus
Manickam R   +4 more
europepmc   +1 more source

Electric‐Current‐Induced Phase Transformation in Cu6Sn5 Below Its Equilibrium Transition Temperature

open access: yesAdvanced Science, EarlyView.
Electric current induces a monoclinic‐to‐hexagonal phase transformation in Cu6Sn5 at a measured bulk temperature of ∼120°C, below the equilibrium transition temperature. Ex situ synchrotron x‐ray diffraction, TEM, and matched thermal controls show that current stressing promotes the formation of a retained hexagonal η‐phase post‐stress state not ...
Shih‐kang Lin   +3 more
wiley   +1 more source

Eco‐Geography Reverses Dominant AMR Reservoirs in Klebsiella pneumoniae: Integron‐Rich Mobilomes and Cross‐Niche Connectivity

open access: yesAdvanced Science, EarlyView.
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin   +12 more
wiley   +1 more source

Rewiring NADH Metabolism Through NQO1‐Mediated Redox Cycling for Targeted Follicular Lymphoma Therapy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Follicular lymphoma (FL) remains an incurable B‐cell malignancy with high relapse rates, and conventional therapies are often limited by significant toxicity, highlighting the need for novel treatments. We identified that FL exhibits markedly low expression of NAD(P)H: quinone oxidoreductase 1 (NQO1), a key enzyme required for activating ...
Jinxing Zhang   +10 more
wiley   +1 more source

Incidence of pediatric chronic tic disorders and feasibility of using the Massachusetts All-Payer Claims Database, 2012-2016. [PDF]

open access: yesEquity Neurosci
Dy-Hollins ME   +6 more
europepmc   +1 more source

Trace Ru‐Doped PtCuRu@PtRu Core‐Shell Electrocatalyst for CO‐Resilient Methanol Oxidation

open access: yesAdvanced Science, EarlyView.
We engineered a trace Ru‐doped PtCuRu@PtRu core‐shell nanostructure. This design exploits lattice mismatch‐induced compressive strain between the PtCuRu ternary core and trace Ru‐doped Pt‐rich shell, systematically downshifting the Pt d‐band center to weaken *CO adsorption energetics.
Tianrui Xue   +7 more
wiley   +1 more source

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