Results 191 to 200 of about 949,450 (246)

A Case Report of Distal Femur Fungal Osteomyelitis. [PDF]

Cureus
M V, Tavfiq M, Harshavardhan G, Suriyakumar S.   +3 more
europepmc   +1 more source

RBM12 Maintains Glioma Stem Cells by Activating Amino Acid‐Dependent mTORC1 Signaling via SLC7A5 mRNA Stabilization

Advanced Science, EarlyView.
This study shows that in glioma stem cells (GSCs), RBM12 recruits ALKBH5 to remove m6A from SLC7A5 transcripts, thereby enhancing mRNA stability, which elevates large neutral amino acid (LNAA) levels and activates mTORC1, promoting GSC proliferation, self‐renewal, and tumor growth.
Hong Lei, Wenlong Luo, Shu Zhou, Lihao Wan, Peng Ling, Zhihua Huang, Zhihua Qian, Chenfei Lu, Mengyue Guo, Zhen Xue, Jun Qin, Ningwei Zhao, Jianghong Man, Wenchao Zhou, Zhiqiang Dong, Shutong Xu, Zhipeng Zhou, Xiuxing Wang, Weiwei Tao   +18 more
wiley   +1 more source

Bronchonodal fistula: An uncommon complication of tuberculosis. [PDF]

Rev Soc Bras Med Trop
Marchiori E, Hochhegger B, Mançano AD, Zanetti G.   +3 more
europepmc   +1 more source

Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276

Advanced Science, EarlyView.
WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan, Ruimin Chang, Meng Zhang, Qian Dong, Guanxiong Zhang, Xiang Chen, Mingliang Chen, Lixia Lu, Xiaowei Liang, Yeye Guo, Juan Su   +10 more
wiley   +1 more source

Diffuse Large B-Cell Lymphoma Presenting With Superior Vena Cava Syndrome and Recurrent Pleural Effusions in a Patient With Angelman Syndrome: A Case Report. [PDF]

Cureus
Khalid A, Matejuk S, Chaeli Van Der Zijp-Tan A, Van Horn N, Jiang K, Fouty B.   +5 more
europepmc   +1 more source

eEF1G Orchestrates Translation to Ensure Meiotic Progression in Transcriptionally Quiescent Spermatocytes

Advanced Science, EarlyView.
eEF1G supports translation elongation of meiotic mRNAs in transcriptionally quiescent leptotene and zygotene spermatocytes. Its depletion in germ cells causes meiotic arrest at the zygotene stage, with defective homologous synapsis and unstable recombination intermediates.
Jianze Xu, Yuwei Hu, Xukun Lu, Yuling Cai, Tongtong Li, Ming Gao, Jinlong Ma, Yuan Gao, Shangming Liu, Zi‐Jiang Chen, Jing Meng, Hongbin Liu, Xiaohua Jiang   +12 more
wiley   +1 more source

Lemierre Syndrome Presenting With Septic Pulmonary Emboli: A Case Report and Diagnostic Challenges. [PDF]

Cureus
Davanellos NI, Paraskeva D, Argiropoulos D, Apergis M, Pachi C, Maragkos I, Palyvos N.   +6 more
europepmc   +1 more source

Counting the Cost: Anticipated Financial Burden and Post-Traumatic Stress Symptoms in Patients Newly Diagnosed with Leukemia and Lymphoma. [PDF]

Mediterr J Hematol Infect Dis
Guolo F, Del Sette P, Riccardi F, Minetto P, Todiere A, Ballerini F, Riva C, Cea M, Lemoli RM, Sarcletti E.   +9 more
europepmc   +1 more source

Pulmonary Pleomorphic Carcinoma Mimicking Small Bowel Obstruction. [PDF]

Cureus
Bhatt AN, Singh B, Patel R, Toscano M, Keshavamurthy J.   +4 more
europepmc   +1 more source