Results 61 to 70 of about 2,763,518 (300)

CEO overconfidence, risk-taking, and firm value: Influence of incentive compensation and financial constraints

open access: yes, 2023
By using the data of firms listed on the three major US stock exchanges—the New York Stock Exchange, Nasdaq Stock Exchange, and American Stock Exchange—this study investigated (1) whether CEO overconfidence increases additional risk-taking and affects ...
Tang, Hui-Wen;Chang, Chong-Chuo
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Parental Perspectives on Financial Incentives for Adolescents: Findings From Qualitative Interviews

open access: yesGlobal Pediatric Health, 2019
Background. Financial incentives are becoming more common to promote health behaviors; however, little is known about the acceptability of incentivizing adolescent health behaviors. Design.
Kera M. Beskin MPH, MBA   +1 more
doaj   +1 more source

Analysis of Revenue Incentive Dynamic Mechanism of Financial Supply Chain from the Perspective of the Internet of Things

open access: yesComplexity, 2021
With the rapid development of society, all walks of life need the support of the Internet of Things, and the financial industry is no exception. This article integrates blockchain technology with supply chain finance and builds a supply chain financial ...
Yue Yin
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Joint Planning and Operation for Renewable- Storage Under Different Financial Incentives and Market Mechanisms

open access: yesIEEE Access, 2020
In this paper, a novel joint planning framework is proposed to coordinate the investment and operation of renewable energy sources and energy storage systems (ESS) in energy and ancillary services markets.
Kunpeng Tian   +3 more
doaj   +1 more source

“Splitting the bill” for conservation: Perceptions and uptake of financial incentives by landholders managing privately protected areas

open access: yesConservation Science and Practice, 2022
Globally, privately protected area (PPA) programs are increasing in size and number. Participating in a PPA program can be fiscally challenging for landholders (e.g., enrollment costs; potential reduction in land value; opportunity costs; costs of ...
Matthew J. Selinske   +4 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

A Dual Characterization of Incentive Efficiency [PDF]

open access: yes, 2001
We show that incentive e cient allocations in economies with adverse se- lection and moral hazard can be determined as optimal solutions to a linear programming problem and we use duality theory to obtain a complete charac- terization of the optima.
Jerez, Belén
core   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

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