Results 71 to 80 of about 2,763,518 (300)

Incentive Problems in Banking Supervision: The European Case [PDF]

open access: yes
This paper discusses the incentive conflicts that arise in banking supervision in the EU in a principal-agent framework, where the regulator is the agent and the taxpayers is the principal.
Schüler, Martin
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Financial and non-financial performance measures and managerial short-term orientation: the interactive effect of performance targets [PDF]

open access: yes
In this paper, I examine the incentive effects of both performance measures and performance targets and the linkages between these two components of the incentive system.
Moers,F.
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Increasing financial incentives can lower the cost of trial recruitment

open access: yesTrials
Monetary incentives are commonly used to help recruit trial participants. Some studies have found greater recruitment with larger incentives, while others have found smaller incentives more cost-effective in terms of cost per participant.
Alan Schwartz   +2 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Financial Decisions, Tax Effect and Investment Performance

open access: yesPrizren Social Science Journal, 2018
The aim of the study is to measure influence of taxation while making financial decisions and predict it with the general application in Turkey. Except for equity returns of financial and negative capital institutions registered in Borsa Istanbul ...
Yasemin Coskun, Selim Bekçioglu
doaj  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Should we pay all smokers to quit smoking? A mixed methods survey exploring New Zealand smokers' perceptions of financial incentives

open access: yesTobacco Induced Diseases, 2018
Background Evidence suggests financial incentives can support smoking cessation among pregnant smokers and for employees in a workplace setting, yet low acceptability may limit the wider implementation of such schemes. The increasing adoption of endgame
Lindsay Robertson   +4 more
doaj   +1 more source

Motivational investments and financial incentives

open access: yesThe Journal of Law, Economics, and Organization
ABSTRACT If firms can invest in the motivation of workers to undertake costly effort, how does that affect the choice of explicit financial incentives? We develop a simple principal–agent model where the standard optimal contract is to offer a bonus that trades off incentive provision versus rent extraction.
Ghatak, Maitreesh   +1 more
openaire   +2 more sources

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