Results 71 to 80 of about 100,138 (310)

Parental Perspectives on Financial Incentives for Adolescents: Findings From Qualitative Interviews

Global Pediatric Health, 2019
Background. Financial incentives are becoming more common to promote health behaviors; however, little is known about the acceptability of incentivizing adolescent health behaviors. Design.
Kera M. Beskin MPH, MBA, Rachel Caskey MD, MAPP   +1 more
doaj   +1 more source

Investigating the mechanism of impact and differential effect of the Quality Premium scheme on antibiotic prescribing in England: a longitudinal study

BJGP Open, 2020
Background: In 2017, approximately 73% of antibiotics in England were prescribed from primary care practices. It has been estimated that 9%–23% of antibiotic prescriptions between 2013 and 2015 were inappropriate.
Philip Emeka Anyanwu, Koen Pouwels, Anne Walker, Michael Moore, Azeem Majeed, Benedict W J Hayhoe, Sarah Tonkin-Crine, Aleksandra Borek, Susan Hopkins, Monsey Mcleod, Céire Costelloe   +10 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

“Splitting the bill” for conservation: Perceptions and uptake of financial incentives by landholders managing privately protected areas

Conservation Science and Practice, 2022
Globally, privately protected area (PPA) programs are increasing in size and number. Participating in a PPA program can be fiscally challenging for landholders (e.g., enrollment costs; potential reduction in land value; opportunity costs; costs of ...
Matthew J. Selinske, Natasha Howard, James A. Fitzsimons, Mathew J. Hardy, Andrew T. Knight   +4 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Joint Planning and Operation for Renewable- Storage Under Different Financial Incentives and Market Mechanisms

IEEE Access, 2020
In this paper, a novel joint planning framework is proposed to coordinate the investment and operation of renewable energy sources and energy storage systems (ESS) in energy and ancillary services markets.
Kunpeng Tian, Weiqing Sun, Dong Han, Ce Yang   +3 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Financial incentives and purchase restrictions in a food benefit program affect the types of foods and beverages purchased: results from a randomized trial

International Journal of Behavioral Nutrition and Physical Activity, 2017
Background This research evaluated the effects of financial incentives and purchase restrictions on food purchasing in a food benefit program for low income people.
Simone A. French, Sarah A. Rydell, Nathan R. Mitchell, J. Michael Oakes, Brian Elbel, Lisa Harnack   +5 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Incentive Problems in Banking Supervision: The European Case [PDF]

This paper discusses the incentive conflicts that arise in banking supervision in the EU in a principal-agent framework, where the regulator is the agent and the taxpayers is the principal.
Schüler, Martin
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