Results 81 to 90 of about 447,852 (292)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Financial Openness, Aggregate Consumption and Threshold Effects

open access: yesPacific Economic Review, 2016
AbstractWe analyse the influence of financial openness on the level of aggregate consumption, a research question that has been left surprisingly unexplored by the previous literature. We construct a complete and balanced panel data set of 88 countries for the period 1980–2010, and then differentiate between four groups of countries.
Marwân-Al-Qays Bousmah, Daria Onori
openaire   +3 more sources

Endogenous Financial and Trade Openness: Political Economy Considerations [PDF]

open access: yes
This paper studies the endogenous determination of financial and trade openness. First, we outline channels leading to two-way feedbacks between the different modes of openness; next, we identify these feedbacks empirically.
Ilan Noy, Joshua Aizenman
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Financial Development, Trade Openness and Economic Growth in North African Countries

open access: yesRomanian Economic Journal, 2014
This contribution investigates the causal interactions between financial development, trade openness and economic growth in a panel of 3 countries of North Africa (Tunisia, Morocco, and Egypt) over the period 1980-2012. Using system Generalized Method of
Nahed Zghidi , Zouheir Abida
doaj  

The impact of financial openness on the earnings of self-employed workers - an empirical evidence from a panel dataset

open access: yesJournal of International Economics and Management, 2022
This paper contributes to the literature on the effect of financial openness by investigating the factors and determinants which drive the income share to self-employed labor during financial liberalization.
Le Thi Thu Huong   +2 more
doaj  

Financial development, trade openness and financial openness: do income levels matter for developing countries? [PDF]

open access: yes
Using a panel of 29 African middle and low income countries with data spanning from 1988 to 2007, we analyze linkages between openness and financial intermediary development when income levels matter. Main findings are four: firstly, openness in the last
Simplice A, Asongu
core   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Determinants of foreign direct investment in SADC region: Case of financial development, institutions and openness

open access: yesSouth African Journal of Economic and Management Sciences
Background: Countries in the Southern African Development Community (SADC) region have experienced low growth coupled with high levels of poverty and inequality.
Sisonke O. Makalima   +2 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

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