Results 51 to 60 of about 4,091,803 (342)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
China’s Macroeconomic Policy Options: A Sectoral Financial Balances Perspective
Studies in Business and Economics, 2016 This paper attempts to discern the macroeconomic policy options open to China after its stock market crash in August 2015. While several facts and figures on different facets of the Chinese economy keep pouring in – high levels household savings, rising ...
Sivramkrishna Sashi
doaj +1 more source
On the equivalence of floating and fixed-strike Asian options [PDF]
, 2000 There are two types of Asian options in the financial markets which differ according to the role of the average price. We give a symmetry result between the floating and fixed-strike Asian options.
Henderson, V, Wojakowski, R M
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Revista Ingenierías Universidad de Medellín, 2010 En este artículo se presentan y aplican diferentes formulaciones matemáticas, exactas y aproximadas, para el cálculo del valor en riesgo (VaR) de algunos portafolios con activos financieros, haciendo especial énfasis en aquellos que contienen opciones ...
Carlos Alexánder Grajales Correa +1 more
doaj
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Company Value, Real Options and Financial Leverage
Acta Polytechnica, 2006 This paper deals with determining of the value of companies and financial leverage. The author tries to find the optimum debt ratio for selected companies in the Czech Republic. The method of yield option extension is used for evaluating a company.
O. Drahovzal
doaj
A CONCEPTUAL FRAMEWORK TO APPLY FINANCIAL ENGINEERING AT THE ENTERPRISE
Baltic Journal of Economic Studies, 2019 The development and continuous complication of financial instruments through the integration of technology and management methods lead to an increasing role of financial engineering to ensure the efficient activity of enterprises.
Viktor Zamlynskyi +2 more
doaj +1 more source
Pricing multivariate currency options with copulas [PDF]
, 2006 Multivariate options are widely used when there is a need to hedge against a number of risks simultaneously; such as when there is an exposure to several currencies or the need to provide cover against an index such as the FTSE100, or indeed any ...
Salmon, Mark H. +3 more
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