Results 61 to 70 of about 4,091,803 (342)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Executive stock options and earnings management in the portuguese listed companies
Revista de Contabilidad: Spanish Accounting Review, 2019 Theoretically, executive stock options align managers’ and shareholders’ interests. However, previous studies have indicated that stock options may engender manager-shareholder conflicts (Jensen, 2005) and create incentives for earnings management (e.g ...
Sandra Alves, Sandra Alves
doaj +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Mенаџмент у хотелијерству и туризму, 2013 F?rward derivative market is a segment of financial market. The business on this market is done by means of financial and commodity derivatives through forward contracts.
Nemanja Pantić, Мiljan Leković
doaj +4 more sources
Financial Derivatives - Option Trade
, 2023 ABSTRACT: This article will give a general review of options trading and examine how they may be utilized as a powerful tool for risk management. Due to this, topics such different kinds of options, trading tactics, and dangers involved in trading options are being discussed as well as the advantages of trading options and how to use them as a risk ...
Jahn, Patrick +2 more
openaire +2 more sources
Portfolio-aspects in real options management [PDF]
, 2001 Real options theory applies techniques known from finance theory to the valuation of capital investments. The present paper investigates further into this analogy, considering the case of a portfolio of real options.
Brosch, Rainer
core
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Financial Product Choices: Does Attribute Preference Help Avoid the Attraction Effect? [PDF]
Studia Psychologica, 2019 The attraction effect occurs when a third option is added to two seemingly equivalent options but it competes against only one of the original options. This increases the likelihood of the dominating option being chosen.
Viera Bačová, Róbert Hanák
doaj +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source