Results 21 to 30 of about 3,936,366 (305)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Effects of Financial Performance and Corporate Social Responsibility on Company Values: Case of Banks Listed on the Indonesia Stock Exchange [PDF]

open access: yes, 2019
This study aims to analyze the effect of financial performance and corporate social responsibility (CSR) on the value of the company at banks listed on the Indonesia Stock Exchange for the period 2013-2017.
Wahongan, L. (Larey)
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Economic and fiscal performance of immigrant-owned firms in Canada

open access: yesEconomic and Social Reports
Canada has one of the highest shares of immigrants among developed countries. In 2021, immigrants made up nearly one-quarter (23.0%) of the population—the largest proportion among G7 nations.
Huju Liu   +3 more
doaj   +1 more source

Effects of operational performance on financial performance [PDF]

open access: yesManagement Science Letters, 2018
Over the past 40 years, global air travel has increased eight-fold: In 1974 air planes carried 421 million people globally. This means that global air travel has been growing up about 5% every year for 4 decades and this trend is expected to continue in ...
Jinpyo Lee
doaj   +1 more source

Downsizing implementation and financial performance [PDF]

open access: yes, 2008
In the present study we explore the relationship between downsizing decisions and corporate financial performance after top management has decided to downsize. Our focus is on the financial consequences arising from the amount of downsizing and the use
Muñoz-Bullón, Fernando   +1 more
core   +1 more source

Inpatient Food Insecurity and Pediatric Hematology Oncology Hospitalization Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Children with cancer and blood disorders are at risk for food insecurity (FI). We aimed to describe the association of inpatient food insecurity (IFI) and hospitalization outcomes among patients admitted to the pediatric hematology oncology service. Of 325 caregivers screened for IFI, 60 (18.6%) screened positive.
Joanna M. Robles   +4 more
wiley   +1 more source

EFFECTIVENESS OF APPLICATION OF ACQUISITION IN ENERGY SECTOR AND MINING COMPANIES IN INDONESIA

open access: yesJurnal Aplikasi Manajemen, 2018
The purpose of this study is to determine the difference in the acquirer’s financial performance as measured by the current ratio of debt to equity ratio of the operating profit margin net profit margin return on investment return on equity between ...
Fatimah Tsaralya Asegaf, Sahala Manalu
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Financial Architecture and Economic Performance: International Evidence [PDF]

open access: yes, 2001
The paper examines the relations between the architecture of an economy's financial system - its degree of market orientation - and economic performance in the real sector.
Tadesse, Solomon
core   +2 more sources

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