Results 51 to 60 of about 11,515,885 (307)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Linking SCM strategy to financial performance: a scenario analysis approach [PDF]
Purpose: This paper proposes a new approach to link supply chain management (SCM) strategy to a company's financial performance. Research Approach: Financial performance results for a company are evaluated and analysed using Du Pont ratio analysis in ...
Elgazzar, S. +3 more
core +3 more sources
Downsizing implementation and financial performance [PDF]
, 2008 In the present study we explore the relationship between downsizing decisions and corporate financial performance after top management has decided to downsize. Our focus is on the financial consequences arising from the amount of downsizing and the use
Muñoz-Bullón, Fernando +1 more
core +1 more source
Evaluation of Public Expenditure in Morocco: An Analysis Using Efficiency Frontiers
EconomiesIn Morocco, the increasing public expenditure on essential sectors, such as education, does not always lead to improved outcomes, highlighting a significant gap between resource allocation and quality enhancement.
Yassin Lhajhouji +2 more
doaj +1 more source
Effects of operational performance on financial performance [PDF]
Management Science Letters, 2018 Over the past 40 years, global air travel has increased eight-fold: In 1974 air planes carried 421 million people globally. This means that global air travel has been growing up about 5% every year for 4 decades and this trend is expected to continue in ...
Jinpyo Lee
doaj +1 more source
Sizing up performance measures in the financial services sector [PDF]
, 2008 The adequate performance of banks, insurers and pension funds is of crucial importance to their private and business customers. The prices and quality of financial products sold by such entities are largely determined by operational efficiency and the ...
Financiering en financiële markten +2 more
core
FINANCIAL RATIOS PREDICTORS OF FINANCIAL SUSTAINABILITY OF THE BANKING SECTOR IN INDONESIA [PDF]
, 2023 This study was conducted to predict the effect of financial ratios on the Financial Sustainability Ratio (FSR). The financial ratios used include Non-Performing Loan (NPL), Loan Deposit Ratio (LDR), Net Interest Margin (NIM), Return on Assets (ROA ...
Adiska Shabrina Sanfa +3 more
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Corporate environmental performance and its impact on financial performance and financial risk: Evidence from Australia [PDF]
, 2014 This thesis consists of four essays on Corporate Environmental Performance (CEP) and its impact on Corporate Financial Performance (CFP). The first essay is entitled “Emission Indices for Hazardous Substances: An Alternative Measure of Corporate ...
Muhammad, Noor
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source