Results 51 to 60 of about 357,743 (260)
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Administrative SciencesWith growing competition in today’s business environments, organizations rely on Performance Measurement Systems (PMSs) to address challenges, assess progress, and enhance performance.
Lubna Q. Owais, Judit T. Kiss
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Non-financial performance measurement by small and medium sized enterprises operating in the hotel industry in the city of Cape Town. [PDF]
African Journal of Hospitality, Tourism and Leisure, 2018 Small and Medium Enterprises (SMEs) operating in the hotel industry in South Africa are perceived to be failing partly due to their reluctance to adopt Non-Financial Performance Measures (NFPMs).
Andile Mjongwana +1 more
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Comparative analysis between the traditional and contemporary approach to efficiency measurement in companies [PDF]
Ekonomija: teorija i praksa, 2020 Nowadays, corporation efficiency measurement is a modern and important trend in various disciplines, such as accounting, finance and especially marketing.
Anđelković Danijela, Đurović Milan
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FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Jurnal Ekonomi dan Bisnis Airlangga, 2010 The purpose of this research is to test the influence of strategy and performance at manufacturing business. Strategy in this research is quality-based manufacturing strategies. Quality-based strategy captures employee involvement, process improvements,
Rahmawati ., Ika Irawati Andayani
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