Results 151 to 160 of about 558,772 (299)

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Investors\u27 Asset Allocations versus Life-Cycle Funds

, 1999
Life-cycle funds, among the newest asset allocation fund offerings, are managed according to investors\u27 time horizons and risk tolerances. Partly in response to the appearance of these funds, we examined the relationships among the risk in individual ...
Schooley, Diane K., Worden, Debra
core  

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Credit risk mitigation in central bank operations and its effects on financial markets - the case of the Eurosystem

, 2006
This paper reviews the role and effects of the collateral framework which central banks, and in particular the Eurosystem, use in conducting temporary monetary policy operations.
Bindseil, Ulrich, Papadia, Francesco
core  

The Internal‐External Synergy of Self‐Reconstructed C/NiFeOOH/SeO42− for Efficient and Stable Seawater Electrolysis

Advanced Science, EarlyView.
This work presents an internal‐external synergy strategy where a C@FeNi2Se4 core‐shell precursor reconstructes in to a C/FeNi2Se4/SeO42− architecture during OER. The inner C stabilizes active sites while the outer SeO42− layer repels Cl−, achieving efficient and stable seawater oxidation for over 150 h at 400 mA cm−2.
Zhe Sun, Yitong Yin, Siyuan Liu, Bo Liao, Bing He, Zhaojie Wang, Xiaoqing Lu, Xingheng Zhang   +7 more
wiley   +1 more source

The Faraday Scalpel: Electrochemical Nerve Lesioning Mechanisms Studied in Invertebrate Models

Advanced Science, EarlyView.
Direct‐current produces nerve lesioning through discrete electrochemical reactions. Using hypoxia‐sensitive locust nerves and hypoxia‐tolerant leech nerves, we map three injury pathways: cathodic oxygen reduction, cathodic alkalization, and anodic chloride oxidation. These findings establish electrochemical lesioning—the “Faraday Scalpel”—as a precise,
Petra Ondráčková, Jan Švec, Marie Jakešová, Jiří Ehlich, Imrich Gablech, Eric Daniel Głowacki   +5 more
wiley   +1 more source

Tuning Desolvation Kinetics with Perovskite‐Type Ion‐Conductive Modulators toward Low‐Temperature Zn Metal Batteries

Advanced Science, EarlyView.
A strategy of constructing perovskite‐type ion‐conductive interphase modulation layer is proposed to break down ion‐dipole interactions of [Zn(H2O)x]2+ to promote Zn2+ desolvation and diffusion kinetics against dendrite growth and active water‐induced hydrogen evolution reactions.
Wenbin Wang, Xiaomin Cheng, Jing Zhang, Shuang Cheng, Zhenjiang Cao, Caiyin You, Yongzheng Zhang, Hao Li, Bixian Chen, Qinghua Guan, Yixiang Shi, Huihua Li, Qingbo Xiao, Hongzhen Lin, Jian Wang   +14 more
wiley   +1 more source

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

Advanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao, Victor Fernandez‐Gonzalez, Xiaochuan Wang, Blake Pylipow, Claudia Herrera, Xiaohu Xia   +5 more
wiley   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Ambient Hydrocarbonylation of Olefins Enabled by Visible‐Light

Advanced Science, EarlyView.
A novel photo‐induced methodology for hydrocarbonylation has been established, resolving the inherent conflicts between competitive olefin and CO insertion in traditional methods that necessitate harsh conditions. Accordingly, an efficient and versatile hydrocarbonylation of olefins enabled by visible‐light irradiation under ambient conditions has been
Hongchi Liu, Tianze Zhang, Hanmin Huang
wiley   +1 more source